Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 15,500 | |||
5 mg | 在庫あり | ¥ 37,500 | |||
10 mg | 在庫あり | ¥ 57,000 | |||
25 mg | 在庫あり | ¥ 102,500 | |||
50 mg | 在庫あり | ¥ 151,500 | |||
100 mg | 在庫あり | ¥ 215,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 59,500 |
説明 | Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,. |
In vivo | Adenosine amine congener (ADAC) was most effective in the first 24 hours after noise exposure at doses >50 μg/kg, providing up to 21 dB protection (averaged across 8-28 kHz). Pharmacokinetic studies demonstrated a short (5 min) half-life of ADAC in plasma after intravenous administration without detection of degradation products. |
動物実験 | Adenosine amine congener (ADAC)??(25-300 μg/kg) was administered intraperitoneally to Wistar rats (8-10 weeks old) at intervals (6-72 hours) after exposure to traumatic noise (8-16 kHz, 110 dB sound pressure level, 2 hours). Hearing sensitivity was assessed using auditory brainstem responses (ABR) before and 12 days after noise exposure. Pharmacokinetic studies investigated ADAC concentrations in plasma after systemic (intravenous) administration[1]. |
別名 | ADAC |
分子量 | 576.6 |
分子式 | C28H32N8O6 |
CAS No. | 96760-69-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 31.25 mg/mL (54.20 mM)
You can also refer to dose conversion for different animals. 詳細
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Adenosine amine congener 96760-69-9 GPCR/G Protein Neuroscience Adenosine Receptor P1 receptor otoprotective loss hearing Inhibitor apoptotic injury systemic A1-adenosine Cochlear inhibit Ca2+ neuroprotective ADAC inhibitor