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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T1973 | PFI-4 | PFI4 | Epigenetic Reader Domain |
PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor. | |||
T7736 | 2-Chloroadenosine | Adenosine Receptor | |
2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively) | |||
T21616 | L-006235 | L 006235 | Cysteine Protease |
L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM. | |||
T1867 | Otenaproxesul | ATB 346 | Apoptosis , COX |
Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity. | |||
T7683 | Adenosine amine congener | ADAC | Adenosine Receptor |
Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,. | |||
T1812 | KX1-004 | KX1 004,KX1004 | Src |
KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK. | |||
T8528 | AC1903 | TRP/TRPV Channel | |
AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss. | |||
T11394 | GFB-8438 | TRP/TRPV Channel | |
GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively). | |||
T1952 | MK-2206 dihydrochloride | MK-2206 2HCl | Apoptosis , Akt , Autophagy |
MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor a... | |||
T126237 | Cynoglossamine | ||
Cynoglossamine is a useful organic compound for research related to life sciences and the catalog number is T126237. | |||
T28232 | Oleoylestrone | Estrone 3-oleate,MP 101,MP-101,MP101 | Antioxidant |
Oleoylestrone (MP-101) is present in plasma and adipose tissue, has potential antioxidant effects, induces loss of body fat in rats, and can be used for weight loss. | |||
T6572 | Lorcaserin HCl | 5-HT Receptor | |
Lorcaserin is a selective serotonin agonist that has been recently approved as a weight loss agent. | |||
T69526 | PF-07258669 | Melanocortin Receptor | |
PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite. | |||
T15014 | CTPB | Histone Acetyltransferase | |
CTPB is a potent p300 histone acetyltransferase (HAT) activator that can be used in the preparation of hair growth promoters and/or hair loss treatments. | |||
T72947 | JBSNF-000028 | JBSNF-000028 free base | Others |
JBSNF-000028 is an orally active and potent nicotinamide N-methyltransferase (NNMT) inhibitor with inhibitory effects on human NNMT (hNNMT), monkey NNMT (mkNNMT), and mouse NNMT (mNNMT) with IC50s of 0.033 μM, 0.19 μM, a... | |||
T71704 | Navamepent | RX-10045 | Others |
Navamepent (RX-10045) is an analog of resolvin E1 (a dietary-3 polyunsaturated fatty acid metabolite), which has potent anti-inflammatory activity that reduces corneal inflammation, epithelial damage, and accelerates cor... | |||
T15679 | L 152804 | Neuropeptide Y Receptor | |
L 152804 is a specific antagonist of the neuropeptide Y Y5 receptor and modulates food intake and energy expenditure thus causing weight loss in diet-induced obese mice. | |||
T76763 | Teplizumab | PRV-031,MGA-031 | Others |
Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes. | |||
T24695 | Quinabactin | LC-66C6,ABA mimics 1,AM1,LC66C6,LC 66C6 | Others |
Quinabactin(LC-66C6) is a potent sulfonamide abscisic acid ABA agonist.Quinabactin promotes guard cell closure, inhibits water loss, suppresses seed germination, and improves drought tolerance in adult Arabidopsis thalia... | |||
TP2486 | Myristoyl Hexapeptide-16 Acetate | Myristoyl Hexapeptide-16 Acetate(959610-54-9 Free base) | Others |
Myristoyl Hexapeptide-16 Acetate is categorized as a protein-stimulating peptide, which means it can help skin's surface look better and become more resistant to moisture loss. | |||
T8469 | LQZ-7I | Survivin | |
LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors | |||
TP2363L | Acetyl tetrapeptide-2 Acetate | Acetyl tetrapeptide-2 Acetate(757942-88-4 Free base) | Others |
Acetyl tetrapeptide-2 Acetate is most commonly used as a skin conditioner. Acetyl tetrapeptide-2 Acetate is done by compensating for hormone loss in the skin, especially collagen, providing somewhat of a plumping effect ... | |||
T0782 | Benzthiazide | Aquatag,Lemazide,Dihydrex | Carbonic Anhydrase |
Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted ... | |||
T2213 | Terconazole | Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,R42470 | Antifection , Antifungal |
Terconazole (Terazol 7) is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damag... | |||
T9573 | GSK3685032 | DNA Methyltransferase | |
GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM). The inhibitory effect is time-independent and reversible. GSK3685032 induces loss of DNA methylation and transcriptional activation and inhibits c... | |||
T69760 | TT-10 | TAZ-K | YAP |
TT-10 (TAZ-K), an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity, has potential application in heart disease research, specifically for conditions characterized by loss o... | |||
T77478 | Milatuzumab | hLL1,MEDI-115 | Others |
Milatuzumab (MEDI-115) is a humanized monoclonal antibody against CD74. Milatuzumab promotes the production of free radical oxygen and the loss of mitochondrial membrane potential, reduces CD20/CD74 aggregates and cell a... | |||
T22361 | Mepivacaine | Carbocaine | Sodium Channel |
Mepivacaine (Carbocaine) is an amide compound for local anaesthesia that causes transient loss of self-consciousness in humans or animals. mepivacaine acts by binding to specific voltage-gated sodium channels in nerve ce... | |||
T0030 | Bupivacaine hydrochloride | Vivacaine,Bupivacaine HCl | Sodium Channel |
Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the vol... | |||
T11098 | Droloxifene | 3-Hydroxytamoxifen | Estrogen Receptor/ERR |
Droloxifene (3-Hydroxytamoxifen), a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells.Fluroxifene has anti-estrogen and anti... | |||
T0802 | Procaine hydrochloride | Novocaine HCl,Procaine HCl | Histone Demethylase , 5-HT Receptor , DNA/RNA Synthesis , Sodium Channel , NMDAR , AChR |
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel... | |||
T4681 | T863 | DGAT-3,DGAT-1 inhibitor | Acyltransferase , Transferase |
T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis... | |||
T9657 | FiVe1 | Others | |
FiVe1 is a vimentin binding small molecule that promotes the disintegration and phosphorylation of vimentin in the metaphase, leading to mitotic disasters, polynuclearization, and loss of cancer cell dryness. FiVe1 selec... | |||
T1482 | Ciclopirox | HOE296b | ATPase , Ferroptosis , Antibacterial , Autophagy , Antifungal |
Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. Ciclopirox is a synthetic, broad-spect... | |||
T2188 | Thonzonium Bromide | Proton pump , Antibacterial , Autophagy | |
Thonzonium bromide is a mono-cationic surfactant that is structurally similar to Farnesol as an antimicrobial agent. It inhibits proton transport in a dose-dependent manner (EC50=69 μM). It inhibits RANKL-induced osteocl... | |||
T3627 | IQ-1S free acid | IQ-1,IQ-1S,IQ-1S (free acid) | NF-κB , JNK |
IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can se... | |||
T1290 | Oxiconazole nitrate | Ro 13-8996 | Others , Antibiotic , Antifection , Antifungal |
Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fully elucidated, oxiconazole... | |||
T72662 | NMDAR/TRPM4-IN-2 | ERK , TRP/TRPV Channel , NMDAR , iGluR | |
NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR/TRPM4-IN-2 has neuroprot... | |||
TP1895L1 | KYL acetate(676657-00-4 free base) | Ephrin Receptor | |
KYL acetate is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP... | |||
T73415 | Miclxin | DS37262926 | Wnt/beta-catenin |
Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via β-catenin.Miclxin is a potent inhibitor of mutant β-catenin, which is involved in the Wnt sign... | |||
T3934 | Isavuconazonium sulfate | Antifungal | |
Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51), wh... | |||
TP1924L1 | ZIP acetate(863987-12-6 free base) | PKC | |
ZIP acetate is a novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampa... | |||
T61268 | Vutiglabridin | HSG4112 | Phosphatase |
Vutiglabridin (HSG4112) is a novel and safe modulator of PON2, a racemic compound. vutiglabridin is an optimized structural analogue of Glabridin and is superior to Glabridin in terms of weight loss and chemical stabilit... | |||
T24898 | Trifenagrel | BW-325U,BW 325U,BW325U | |
Trifenagrel is an antithrombotic. It has been found to produce less gastric irritation and fecal blood loss in humans. | |||
T20845 | Kopexil | Mexoryl SAG,Aminexil | |
Kopexil, an N-oxide, is used to treat hair loss. | |||
T69642 | FT385 | ||
FT385 is a novel USP30 inhibitor, recapitulating genetic loss of USP30 and setting the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation. | |||
T26317 | VEC6 | VEC-6,NSC11435,NSC 11435,NSC-11435,VEC 6 | |
VEC6 is a VEZF1–DNA interaction inhibitor that recapitulates RhoB loss in ischaemic retinopathy. | |||
T25607 | Lamifiban | Ro-44-9883/000,Ro 44-9883/000,Ro44-9883/000 | |
Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass. | |||
T33815 | ORC-13661 HCl | ORC 13661,BPN13661,ORC13661,ORC-13661,BPN 13661,BPN-13661 | |
Orc-13661 (BNP-13661) is a potent and well-tolerated oral active protective agent for the prevention of aminogrogycoside-induced hearing loss. | |||
TP1439 | AZP-531 | ||
Azp-531 is a disacylated ghrelin used to improve blood sugar control and weight loss. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5S2129 | Sciadopitysin | TNF , NF-κB | |
Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o... | |||
T1287 | Synephrine | Oxedrine | Endogenous Metabolite , Adrenergic Receptor |
Synephrine (Oxedrine) is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma. | |||
T5575 | Cycloastragenol | Cyclogalegenol,Astramembrangenin | Epigenetic Reader Domain , Telomerase |
Astramembrangenin (Cycloastragenol (Astramembrangenin)) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloastragenol (CAG) may have a novel therape... | |||
TN1494 | Cimicifugoside H-1 | Others | |
Cimicifugoside H1 shows the protective function to cerebral neuron during cerebral ischemia. | |||
T6688 | Synephrine hydrochloride | Oxedrine hydrochloride,Synephrine HCl | Endogenous Metabolite , Adrenergic Receptor |
Synephrine hydrochloride (Oxedrine hydrochloride) is an agonist that acts on sympathomimetic α-adrenergic receptor (AR). | |||
T4110 | Perivine | Perivin | Others |
Perivine (Perivin) may resolve the instability of the retinoblastoma-associated proteins (RbAp48) complex and thus be used in Alzheimer's disease therapy. Perivine, vobasine, coronaridine and dichomine show hypotensive a... | |||
TN5834 | Loroglossin | ||
Loroglossin is a natural product for research related to life sciences. The catalog number is TN5834 and the CAS number is 58139-22-3. | |||
TJS0856 | Dalbergin | 6-Hydroxy-7-Methoxy-4-Phenylcoumarin | Others |
1. Dalbergin (6-Hydroxy-7-Methoxy-4-Phenylcoumarin) exhibits similar bone conserving effect against bone-loss as estradiol treatment, it as a therapeutic candidate against postmenopausal osteoporosis. 2. Dalbergin preven... | |||
T0146 | Tioconazole | UK-20349,Vagistat | Antibiotic , Antifection , Antifungal |
Tioconazole (Vagistat) is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and pr... | |||
T11590 | (-)-Hydroxycitric acid | Garcinia acid | ATP Citrate Lyase |
(-)-Hydroxycitric acid (Garcinia acid) (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia. It is a potent and competitive inhibitor of ATP citrate lyase. (-)-Hydroxycitric acid suppresses fatty aci... | |||
T3S1873 | Talatisamine | Potassium Channel | |
1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talat... | |||
T0522 | Diammonium Glycyrrhizinate | Glycyrrhizin | Dehydrogenase |
Diammonium Glycyrrhizinate (Glycyrrhizin) , an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-β-hydroxysteroid dehydrogenase and ... | |||
T6S0139 | Neobavaisoflavone | Apoptosis , DNA/RNA Synthesis | |
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si... | |||
T6S0071 | Fraxinellone | HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1 | |
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding... | |||
T3243 | Betaine | Abromine,glycine betaine,oxyneurine,trimethylglycine,lycine | Others , Endogenous Metabolite |
Betaine (trimethylglycine) is a methyl derivative of glycine first isolated from sugar beets. It has been shown to have potential benefits for fighting heart disease, improving body composition, and helping promote muscl... | |||
T40834 | 5-Hydroxymethyl-2'-deoxycytidine | 5hmdC | PARP |
5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.5-Hydroxy... | |||
T4S1962 | Beta-Asarone | Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin | NF-κB , JNK |
1. beta-Asarone (Cis-Isoelemicin) may be a potential preventive drug for Alzheimer's disease. 2. Beta-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in SAMP8 mice. 3. The co-administration of be... | |||
T11589 | Hydroxycitric acid tripotassium hydrate | Potassium citrate monohydrate | ATP Citrate Lyase , HIF/HIF Prolyl-Hydroxylase , HIF |
Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation, and anti-tumor effects. Hydroxycitric acid tr... | |||
T3849 | Kinsenoside | (+)-Kinsenoside | Apoptosis , Nrf2 |
Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities. Kinsenoside could be useful for repairing beta cells in pancreatic islet injury as well as improving its function, it cou... | |||
T3673 | Mollugin | Rubimaillin | HER , JAK |
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr... | |||
T6S1966 | Curculigoside | Curculigoside A | Antioxidant , NF-κB , JAK , STAT |
1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disord... | |||
T5S1097 | Neferine | (R)-1,2-Dimethoxyaporphine,(-)-Neferine | Apoptosis , NF-κB , Autophagy |
1. Neferine ((-)-Neferine) has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase the efficacy of DOX and to a... | |||
T4723 | D-Tagatose | D-(-)-Tagatose,d-tagatos | Others , Endogenous Metabolite |
D-Tagatose (D-(-)-Tagatose), a rare natural hexoketose, is an isomer of d-galactose. D-Tagatose occurs naturally in Sterculia setigera gum, and it is also found in small quantities in various foods such as sterilized and... | |||
T4S0969 | Obtusifolin | Antioxidant , NF-κB | |
1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be... | |||
T4776 | Glycerol | Glycerin | Endogenous Metabolite |
Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol... | |||
T16285 | Neosolaniol | Potassium Channel | |
Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response. | |||
TN1778 | Isoformononetin | IL Receptor , Antifection | |
Isoformononetin shows fungitoxic activity against Cladosporium sphaerospermum; it also has immunomodulatory activity, it inhibits the differentiation of Th17 cells and B-cell lymphopoesis to promote osteogenesis in estro... | |||
T10196 | 7α-Hydroxy-4-cholesten-3-one | Others | |
TN4639 | Neolitsine | Others | |
Neolitsine has anthelmintic activity, it exhibits EC90 values (concentration at which 90% loss of larval motility is observed) of 6.4 microg/mL.Neolitsine and dicentrine have potent vasorelaxing effects on precontracted ... | |||
TN3754 | Dalbergiphenol | Others | |
Dalbergiphenol shows antiosteoporotic activity, dalbergiphenol treatment can effectively prevent OVX-induced increase in bone loss and decrease in bone strength possibly by increasing osteoblastic activities and by decre... | |||
T75425 | Synephrine hemitartrate | ||
Synephrine hemitartrate (Oxedrine), an alkaloid extracted from Citrus aurantium, functions as both an α-adrenergic and β-adrenergic agonist. As a sympathomimetic compound, it has applications in weight loss [1] [2]. | |||
TN4519 | Mesuaxanthone A | Others | |
Mesuaxanthone A and mesuaxanthone B are two yellow pigments.They produce varying degrees of C.N.S. depression characterised by ptosis, sedation, decreased spontaneous motor activity, loss of muscle tone, potentiation of ... | |||
TN3802 | Dehydrodiconiferyl alcohol | Estrogen/progestogen Receptor | |
Dehydrodiconiferyl alcohol (DHCA) is a lignan isolated from calabash that inhibits osteoclast differentiation and oophorectomy induced bone loss by acting as an estrogen receptor agonist. | |||
T35532 | Galegine hydrochloride | ||
Galegine hydrochloride, a guanidine derivative derived from G. officinalis, plays a role in inducing weight loss in mice and has contributed to the development of biguanides, including metformin and phenformin. This comp... | |||
TN4937 | Sambutoxin | Others | |
Sambutoxin, a new mycotoxin produced by toxic Fusarium isolates obtained from rotted potato tubers, it can cause toxic effects in rats, including body weight loss, feed refusal, hemorrhage in the stomach and intestines, ... | |||
TN3587 | Capillarisin | MMP , ERK , IL Receptor , BCL , VEGFR , TNF , NOS , NF-κB , TLR , MAPK , COX , DNA/RNA Synthesis , Prostaglandin Receptor , JNK , STAT | |
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells, it inhibits cancer cell growth of osteosarcoma cells by ... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPJ-00549 | MANSC1 Protein, Human, Recombinant (His) | Human | Human Cells |
MANSC domain-containing protein 1(MANSC1) is encoded by MANSC1 gene. MANSC1 is a Single-pass type I membrane protein which contains 1 MANSC domain. It is widely expressed in many tissues and mainly located in membrane. | |||
TMPY-02030 | CD82 Protein, Human, Recombinant (His) | Human | HEK293 |
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetras... | |||
TMPY-04153 | RNF43 Protein, Human, Recombinant (His) | Human | HEK293 |
RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr... | |||
TMPY-03364 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant | Human | HEK293 |
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro... | |||
TMPY-01009 | TGFBI Protein, Human, Recombinant (His) | Human | HEK293 |
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several ... | |||
TMPY-02726 | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro... | |||
TMPY-03674 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro... | |||
TMPY-01897 | PRSS3 Protein, Human, Recombinant (His) | Human | HEK293 |
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on... | |||
TMPY-01630 | Syndecan-1 Protein, Human, Recombinant (His) | Human | HEK293 |
Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development... | |||
TMPY-02767 | TPP1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Tripeptidyl-peptidase 1 (TPP1 / CLN2) is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activit... | |||
TMPY-03762 | E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Cadherins are calcium-dependent cell adhesion proteins which preferentially interact with themselves in a homophilic manner in connecting cells, and thus may contribute to the sorting of heterogeneous cell type. E-cadher... | |||
TMPY-05435 | ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis... | |||
TMPY-00841 | IL-13RA2 Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpre... | |||
TMPY-01298 | CADM1 Protein, Human, Recombinant (His) | Human | HEK293 |
Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular... | |||
TMPY-02327 | HGF Protein, Human, Recombinant | Human | CHO |
Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by ... | |||
TMPY-03290 | HGF Protein, Mouse, Recombinant | Mouse | HEK293 |
Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by ... | |||
TMPY-02431 | BCL-XL Protein, Human, Recombinant (His) | Human | E. coli |
B-cell lymphoma-extra large (Bcl-xl) is a transmembrane molecule in the mitochondria. Bcl-xL (BCL2L1), belongs to the Bcl-2 family. Members of the bcl-2 family encode proteins that function either to promote or to inhibi... | |||
TMPY-01101 | Coagulation factor X/F10 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the... | |||
TMPK-01030 | LRRN1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction be... | |||
TMPY-03876 | PTGFRN Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
EWI-F, also known as PTGFRN, is inversely related to the loss of CD9. Its expression correlates with the metastatic status of hLT. EWI-F inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP rece... | |||
TMPY-04732 | Fibrinogen Gamma Chain Protein, Human, Recombinant | Human | Yeast |
Loss of function mutations in FGG have been associated with fibrinogen deficiency. FGG mRNA was expressed abnormally in HCC and elevated plasma fibrinogen may serve as a useful predictor of clinical progression of HCC pa... | |||
TMPK-01010 | CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPK-01183 | CDCP1 Protein, Human, Recombinant (aa 30-368, His) | Human | HEK293 |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPK-00635 | CDCP1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPK-00097 | FGF-21 Protein, Human, Recombinant (mFc & Avi) | Human | HEK293 |
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the document... | |||
TMPJ-00243 | Serpin B6 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in th... | |||
TMPY-03227 | CISD1 Protein, Human, Recombinant (His) | Human | E. coli |
Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson's disease (PD), the loss of mitoNEET (CISD1), an iron-sulfur containing protein that regulates mitochondrial bioe... | |||
TMPY-05067 | Fibrinogen Gamma Chain Protein, Mouse, Recombinant | Mouse | Yeast |
Loss of function mutations in FGG have been associated with fibrinogen deficiency. FGG mRNA was expressed abnormally in HCC and elevated plasma fibrinogen may serve as a useful predictor of clinical progression of HCC pa... | |||
TMPH-02646 | Erythroferrone Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase... | |||
TMPY-00368 | ALR Protein, Human, Recombinant (His) | Human | HEK293 |
Alterations in GFER gene have been associated with progressive mitochondrial myopathy, congenital cataracts, hearing loss, developmental delay, lactic acidosis and respiratory chain deficiency in 3 siblings born to consa... | |||
TMPY-00483 | Parvalbumin/PVALB Protein, Human, Recombinant (His) | Human | E. coli |
Parvalbumins (PVALBs) are particularly abundant in the fast-contracting muscles and correlate positively with muscle relaxation speed in amphibians and fishes. The loss of PVALB plays a role in the pathogenesis of thyroi... | |||
TMPK-00540 | Serpin F2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Large-pool solvent/detergent (SD) plasma for transfusion exhibits reduced alpha 2-antiplasmin (alpha2-AP; SERPINF2) functional activity. The reason for the loss of alpha2-AP has not been described and could be due to the... | |||
TMPK-00738 | EVA-1/MPZL2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epitheli... | |||
TMPK-00737 | EVA-1/MPZL2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epitheli... | |||
TMPY-04267 | MSH2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
MSH2 is a key DNA mismatch repair protein, which plays an important role in genomic stability. In addition to its DNA repair function, MSH2 serves as a sensor for DNA base analogs-provoked DNA replication errors and bind... | |||
TMPK-00098 | FGF-21 Protein, Human, Recombinant (mFc & Avi), Biotinylated | Human | HEK293 |
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the document... | |||
TMPK-01256 | CDCP1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPK-01182 | CDCP1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPK-01181 | CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPK-01255 | CDCP1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated | Cynomolgus | HEK293 |
Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ... | |||
TMPY-02242 | Serpin B6 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-... | |||
TMPH-01301 | Erythroferrone Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase... | |||
TMPY-04149 | RNF43 Protein, Human, Recombinant (hFc) | Human | HEK293 |
RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr... | |||
TMPH-01305 | ER beta Protein, Human, Recombinant (His) | Human | Yeast |
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.; Lacks ... | |||
TMPH-01304 | ER beta Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.; Lacks ... | |||
TMPK-00761 | B2M/beta 2-Microglobulin Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
The genetic and functional analysis of β2-microglobulin (B2M), a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched pat... | |||
TMPJ-00670 | YKT6 Protein, Human, Recombinant (His) | Human | E. coli |
Synaptobrevin Homolog YKT6 (YKT6) is an enzyme that belongs to the Synaptobrevin family. YKT6 contains a longin domain and a v-SNARE coiled-coil homology domain. YKT6 is highly conserved from yeast to human and it can fu... | |||
TMPJ-00084 | RBP4 Protein, Human, Recombinant | Human | E. coli |
Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue, and is associated with insulin resistance.... | |||
TMPK-01158 | Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulat... | |||
TMPY-01659 | SDPR Protein, Mouse, Recombinant (aa 2-180, His) | Mouse | E. coli |
Serum deprivation-response protein, also known as Phosphatidylserine-binding protein, Cavin-2 and SDPR, is a member of the PTRF / SDPR family. SDPR is highly expressed in heart and lung, and expressed at lower levels in ... | |||
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A unique collection of 2247 anti-obesity compounds for high throughput and high content screening; | |||
L2150 | Anti-Cancer Drug Library | 3080 compounds | |
A unique collection of 3080 anticancer drugs for high throughput screening (HTS) and high content screening (HCS); | |||
L2160 | Anti-Cancer Active Compound Library | 3188 compounds | |
A unique collection of 3188 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L2100 | Anti-Cancer Compound Library | 7234 compounds | |
A unique collection of 7234 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L2120 | Anti-Cancer Clinical Compound Library | 2545 compounds | |
A unique collection of 2545 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L8200 | Anti-Aging Compound Library | 3279 compounds | |
A unique collection of 3279 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L2110 | Anti-Cancer Approved Drug Library | 1779 compounds | |
A unique collection of 1779 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS); | |||
L8710 | Cuproptosis Compound Library | 400 compounds | |
TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases. | |||
L2180 | Anti-Cancer Compound Library Plus | 1468 compounds | |
Well-chosen 1468 anti-tumor compounds with unique structures; | |||
L9830 | Anti-Parkinson's Disease Compound Library | 857 compounds | |
A unique collection of 857 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS. | |||
L6020 | Selectable Natural Product Library | 16627 compounds | |
A unique collection of 16627 pure natural products with diverse structures and sources covering various plant, animal, and microbe species; | |||
L6030 | Natural Product Derivatives Library for CADD | 163000 compounds | |
Large quantity: contains 163,000 natural product derivatives and the number is continuously updating; | |||
L2630 | Neuronal Differentiation Compound Library | 672 compounds | |