Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
50 mg | 在庫あり | ¥ 8,500 | |||
100 mg | 在庫あり | ¥ 11,500 | |||
200 mg | 在庫あり | ¥ 17,500 | |||
500 mg | 在庫あり | ¥ 27,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy. |
In vivo | Aminoguanidine ameliorates neonatal hypoxic-ischemic brain damage and that temporal profiles of NO correlated with the neuroprotective effect of aminoguanidine. Neuroprotection by AG is attributable to suppression of NO produced by iNOS after the end of the hypoxic period, during the reoxygenation phase. The half-life of AG is estimated to be between 6 and 8 h in vivo and approximately 4.4 h in human with normal renal function.AG is also an inhibitor of the formation of advanced glycation end products. Systematically administered advanced glycation end product–modified BSA increases cerebral infarct size in an adult rat, which is attenuated by AG[2]. |
別名 | Imino semicarbazide, Pimagedine hydrochloride, CP-12009-18 tartrate, Hydrazinecarboximidamide, Guanyl hydrazine, Pimagedine |
分子量 | 110.55 |
分子式 | CH6N4·HCl |
CAS No. | 1937-19-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (452.28 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: 20 mg/mL (180.9 mM)
You can also refer to dose conversion for different animals. 詳細
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Aminoguanidine hydrochloride 1937-19-5 Immunology/Inflammation NO Synthase NOS Aminoguanidine Hydrochloride Nitric oxide synthases GER 11 GER-11 Imino semicarbazide Pimagedine hydrochloride CP-12009-18 tartrate Hydrazinecarboximidamide Aminoguanidinium CP-12009-18 Tartrate inhibit GER11 Inhibitor Pimagedine Hydrochloride Guanyl hydrazine Pimagedine Aminoguanidine inhibitor