Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.1 When examined for its potential use in Alzheimer's disease treatment, auraptene was shown to inhibit β-secretase (BACE1) activity with an IC50 value of 345.1 μM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 7,000 | |||
10 mg | 在庫あり | ¥ 9,000 | |||
25 mg | 在庫あり | ¥ 13,500 | |||
50 mg | 在庫あり | ¥ 17,500 | |||
100 mg | 在庫あり | ¥ 32,000 | |||
500 mg | 在庫あり | ¥ 78,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.1 When examined for its potential use in Alzheimer's disease treatment, auraptene was shown to inhibit β-secretase (BACE1) activity with an IC50 value of 345.1 μM. |
ターゲット&IC50 | BACE1:345.1 μM. |
植物由来 |
別名 | 7-geranyloxycoumarin |
分子量 | 298.38 |
分子式 | C19H22O3 |
CAS No. | 495-02-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (167.56 mM)
You can also refer to dose conversion for different animals. 詳細
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Auraptene 495-02-3 Neuroscience Proteases/Proteasome BACE MMP inhibit Inhibitor Matrix metalloproteinases 7-geranyloxycoumarin inhibitor