Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
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5 mg | 在庫あり | ¥ 10,000 | |||
10 mg | 在庫あり | ¥ 12,000 | |||
25 mg | 在庫あり | ¥ 23,500 | |||
50 mg | 在庫あり | ¥ 36,500 | |||
100 mg | 在庫あり | ¥ 66,000 | |||
500 mg | 在庫あり | ¥ 159,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,000 |
説明 | Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response. |
In vitro | Azoramide, a dual-function endoplasmic reticulum (ER) modulator, improves ER protein-folding ability and activates ER chaperone capacity to protect cells against ER stress in multiple systems. |
In vivo | In two independent mouse models of obesity, Azoramide exhibits potent antidiabetic efficacy by improving insulin sensitivity and pancreatic β cell function. |
分子量 | 308.83 |
分子式 | C15H17ClN2OS |
CAS No. | 932986-18-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (161.91 mM)
You can also refer to dose conversion for different animals. 詳細
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Azoramide 932986-18-0 Apoptosis PERK mitochondrial function ER protein fold antidiabetic inhibit CERB signaling ER chaperone capacity Inhibitor unfolded protein response DA neurons inhibitor