Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMT-124110 is a selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibited BMP-2 induced protein kinase BIKE with IC50 of 17 nM. BMT-090605 inhibits cyclin G-associated kinase GAK with an IC50 of 99 nM.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 75,500 |
5 mg | 在庫あり | ¥ 183,500 |
10 mg | 在庫あり | ¥ 250,500 |
25 mg | 在庫あり | ¥ 379,000 |
50 mg | 約8-10週間 | ¥ 512,000 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 219,000 |
説明 | BMT-124110 is a selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibited BMP-2 induced protein kinase BIKE with IC50 of 17 nM. BMT-090605 inhibits cyclin G-associated kinase GAK with an IC50 of 99 nM. |
ターゲット&IC50 | AAK1:0.9 nM, GAK:99 nM |
In vitro | BMT-124110 presents a cellular IC50 of 3.2 nM for AAK1[1]. |
In vivo | BMT-124110 is added directly to the spine by microion electrophoresis. Wind-induced activity decreased in 10 of the 14 animals.[1] |
分子量 | 369.46 |
分子式 | C21H27N3O3 |
CAS No. | 1679371-59-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (74.43 mM)
You can also refer to dose conversion for different animals. 詳細
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BMT-124110 1679371-59-5 Neuroscience AAK1 (AP2 associated kinase 1) BMT124110 BMT 124110 Inhibitor inhibitor inhibit