Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 11,000 | |||
10 mg | 在庫あり | ¥ 17,500 | |||
25 mg | 在庫あり | ¥ 37,500 | |||
50 mg | 在庫あり | ¥ 60,500 | |||
100 mg | 在庫あり | ¥ 89,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a. |
ターゲット&IC50 | TET2:73 μM (cell free), TET1:33 μM (cell free) |
In vitro | HT-22 cells were treated with 10 μM Bobcat339 in 1% DMSO for 24 hrs and lysed. Cells treated with Bobcat339 had significantly reduced global 5hmC levels as compared to vehicle control. |
別名 | Bobcat339 hydrochloride |
分子量 | 297.74 |
分子式 | C16H12ClN3O |
CAS No. | 2280037-51-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (151.14 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Bobcat339 2280037-51-4 Chromatin/Epigenetic DNA Methyltransferase Cytosine-based,TET Bobcat339 Hydrochloride epigenetics enzyme Bobcat-339 TET1,TET2 Inhibitor Bobcat 339 Bobcat339 hydrochloride DNA MTases DNMTs inhibit inhibitor