Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 27,000 | |||
5 mg | 在庫あり | ¥ 66,500 | |||
10 mg | 在庫あり | ¥ 104,500 | |||
25 mg | 在庫あり | ¥ 173,000 | |||
50 mg | 在庫あり | ¥ 243,500 | |||
100 mg | 在庫あり | ¥ 328,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 73,000 |
説明 | CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM). |
ターゲット&IC50 | CDK8:3 nM |
In vivo | CDK8-IN-1 displays low systemic clearance, very good exposure, and oral bioavailability. The tmax is 0.25 h by p.o. The values of AUC are 9378, 25952 by i.v., and p.o. respectively. The mean values of Cmax are 9940 μg/L, 12740 μg/L by i.v., and p.o. respectively[1]. |
分子量 | 255.2 |
分子式 | C11H8F3N3O |
CAS No. | 1629633-48-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (352.7 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CDK8-IN-1 1629633-48-2 Cell Cycle/Checkpoint CDK CDK8IN1 CDK-8-IN-1 CDK8 IN 1 Inhibitor inhibitor inhibit