Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CGK733 (CGK 733) is a potent and selective inhibitor of ATM/ATR.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 7,000 | |||
10 mg | 在庫あり | ¥ 12,000 | |||
25 mg | 在庫あり | ¥ 22,500 | |||
50 mg | 在庫あり | ¥ 41,000 | |||
100 mg | 在庫あり | ¥ 81,500 | |||
500 mg | 在庫あり | ¥ 193,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 9,000 |
説明 | CGK733 (CGK 733) is a potent and selective inhibitor of ATM/ATR. |
In vivo | In senescent cells with halted proliferation, treatment with CGK733 leads to the disappearance of senescence-associated beta-galactosidase (SA-β-gal) activity, enabling the cells to proliferate. In aged MCF-7 cells, 24-hour treatment with CGK733 (30 μM) can induce cell death. Furthermore, in various cancer cells, such as MCF-7 and T47D estrogen receptor (ER) positive breast cancer cells, MDA-MB436 ER-negative breast cancer cells, LnCap precursor cancer cells, and HCT116 colon cancer cells, CGK733 (0.6-40 μM) has the capability to inhibit proliferation. |
別名 | CGK 733 |
分子量 | 555.84 |
分子式 | C23H18Cl3FN4O3S |
CAS No. | 905973-89-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (179.9 mM)
You can also refer to dose conversion for different animals. 詳細
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CGK733 905973-89-9 DNA Damage/DNA Repair PI3K/Akt/mTOR signaling ATM/ATR Inhibitor inhibit CGK 733 ATM and RAD3 related Ataxia telangiectasia mutated CGK-733 inhibitor