Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cot inhibitor-2 is a cot (Tpl2/MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-α production in human whole blood with an IC50 of 0.3 μM.
ターゲット&IC50 | TNF-α production (human whole blood):0.3 μM, Cot (Tpl2/MAP3K8):1.6 nM |
分子量 | 539.43 |
分子式 | C26H25Cl2FN8 |
CAS No. | 915363-56-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 36.0 mg/mL (66.7 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Cot inhibitor-2 915363-56-3 Apoptosis MAPK TNF Cot inhibitor2 Cot inhibitor 2 Inhibitor inhibitor inhibit