|
T20470 |
Edetic acid
|
Ethylenediaminetetraacetic acid,EDTA |
Others
|
|
Edetic acid (Ethylenediaminetetraacetic acid) is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity. |
|
T5519 |
Bivalirudin
|
BG-8967,Hirulog-1 |
Thrombin
|
|
Bivalirudin (BG-8967) is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clotting activities. |
|
T0389 |
Dabigatran etexilate
|
BIBR 1048 |
Thrombin
|
|
Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. |
|
T31206 |
Darexaban
|
YM 150,Darexaban, Tanexaban,YM150 |
Factor Xa
|
|
Darexaban (Tanexaban, YM-150) is a direct inhibitor of Factor Xa.Darexaban and Darexaban glucuronide selectively and competitively inhibit FXA and inhibit prothrombin activity at the site of blood clot (thrombus) formati... |
|
T5133 |
Dabigatran Etexilate Mesylate
|
BIBR 1048MS,Dabigatran etexilate methanesulfonate |
Thrombin
|
|
Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI, Ki: 4.5 nM). |
|
T2368 |
Edoxaban Tosylate Monohydrate
|
DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban |
Factor Xa
,
Thrombin
|
|
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention. |
|
T1515 |
Bromindione
|
Fluidane,Halinone |
Others
|
|
Bromindione (Fluidane) is a new anticoagulant. |
|
T9153 |
Picotamide
|
|
Others
|
|
Picotamide has anticoagulant and fibrinolytic properties. |
|
T0360 |
Chlorindione
|
chlophenadione,Indaliton,G-25766 |
|
|
Chlorindione (chlophenadione) is a vitamin K antagonist, a potent anticoagulant compound. |
|
TP1628L |
Activated Protein C (390-404), human acetate
|
Activated Protein C (390-404), human acetate(146340-20-7 Free base) |
APC
|
|
Activated Protein C (390-404), human acetate (Activated Protein C ) inhibits APC anticoagulant activity. |
|
T22246 |
Argatroban Monohydrate
|
|
Thrombin
|
|
Argatroban Monohydrate is a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi. |
|
T0155 |
Argatroban
|
MCI-9038,MD-805,Argipidine |
Thrombin
|
|
|
|
T80792 |
WAY-639228
|
|
Others
|
|
WAY-639228-A has potential antithrombotic and anticoagulant activity for the study of cerebral thrombosis. |
|
T30191L |
Atecegatran TFA
|
Atecegatran TFA(917904-13-3 Free base）,AR-H067637 TFA |
Others
|
|
Atecegatran TFA is often used as an anticoagulant and can be used to treat cardiovascular disease. |
|
T50001 |
Tinoridine
|
ethyl 2-amino-6-benzyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate |
P450
|
|
Tinoridine is a quinoline derivative analog that acts by inhibiting the production of cyclooxygenase-2 (COX-2). It has anti-inflammatory, anti-allergic and anticoagulant activities. |
|
T77690 |
L-Cyclohexylalanine
|
L-3-Cyclohexylalanine,H-Cha-OH,3-Cyclohexyl-L-alanine |
|
|
L-Cyclohexylalanine (L-3-Cyclohexylalanine) is an amino acid analog that binds to the heavy enzyme thioester of the short peptide S synthase.L-Cyclohexylalanine can be used to synthesize anticoagulant decapeptides. |
|
T0372 |
Gabexate mesylate
|
FOY |
Factor Xa
,
Serine Protease
,
Proteasome
|
|
Gabexate mesylate (FOY) is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inh... |
|
T6531 |
Heparin sodium salt
|
Sodium heparinate,Heparin sodium |
Factor Xa
,
Thrombin
,
Autophagy
|
|
Heparin sodium is a sulfated polysaccharide, which belongs to the family of glycosaminoglycans. It is utilized as an anticoagulant and interacted with diverse proteins for numerous important biological activities.Heparin... |
|
T4980 |
Betrixaban maleate
|
|
Factor Xa
|
|
Betrixaban maleate is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa. |
|
T26240 |
Surfen dihydrochloride
|
Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl |
FGFR
,
Antiviral
,
Antibiotic
|
|
Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulphate with antimicrobial and antiviral activity and inhibits anthrax lethal factor, coagulation factor X and let... |
|
T0514 |
Phenindione
|
Rectadione,phenylindandione,Phenylindione |
|
|
Phenindione (Rectadione) is an indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. |
|
T10820L1 |
Ciraparantag acetate
|
Ciraparantag acetate(1438492-26-2 Free base) |
Others
|
|
Ciraparantag acetate, an anticoagulant reversal agent, is a small molecule specifically designed to bind noncovalently by charge-charge interaction to unfractionated heparin and low-molecular-weight heparin. It shows bin... |
|
T1736 |
Apixaban
|
BMS-562247-01 |
Factor Xa
|
|
Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and pr... |
|
T1184 |
Rivaroxaban
|
BAY 59-7939 |
Factor Xa
,
Thrombin
|
|
Rivaroxaban (BAY 59-7939) is an orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both ... |
|
T4341 |
Betrixaban
|
PRT054021 |
Factor Xa
|
|
Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel ... |
|
T77124 |
Osocimab
|
BAY 1213790 |
FXR
|
|
Osocimab (BAY 1213790) is a potent anti-FXIa antibody with a Ki value of 2.4 nM and an EC50 value of 0.2 nM.Osocimab may reduce thrombosis through FXI inhibition.Osocimab is often used as an XI factor inhibitor, has an i... |
|
T0815L |
Warfarin sodium
|
|
|
|
An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, an... |
|
T2368L |
Edoxaban
|
Lixiana |
Factor Xa
,
Thrombin
|
|
Edoxaban (Lixiana) (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K i s of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and is a... |
|
T25835 |
Moxicoumone
|
|
|
|
Moxicoumone is an anticoagulant agent. |
|
T23755 |
AS1468240
|
AS 1468240,AS-1468240 |
|
|
AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity. |
|
T28404 |
Phenyramidol Hydrochloride
|
Vazalmin,Analexin,Firmalgil,Phenyramidol HCl,Betapirin |
|
|
Phenyramidol Hydrochloride is an anticoagulant and analgesic. |
|
T24930 |
Valone
|
AI300366,AI3-00366,AI3 00366 |
|
|
Valone is an anticoagulant. |
|
T71543 |
Difethialone
|
|
|
|
Difethialone is an anticoagulant rodenticide and a vitamin K antagonist. |
|
T23051 |
Nafamostat hydrochloride
|
|
Others
|
|
Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant. |
|
T20616 |
Coumachlor
|
G-23133,Ratilan,G23133,Tomorin,G 23133 |
|
|
Coumachlor, a first-generation anticoagulant rodenticide, blocks the formation of prothrombin and inhibits blood coagulation causing internal haemorrhage. |
|
T27545 |
Hirugen
|
BG 8865,Hirudin dodecapeptide |
|
|
Hirugen is a derivative of hirudin, which is an anticoagulant protein found in leeches. |
|
T23052 |
Nafamostat
|
|
Others
|
|
Nafamostat is a synthetic serine protease inhibitor and is an anticoagulant. |
|
T25909 |
Oxazidione
|
LD 4610,Transidione,LD4610,LD-4610,Amplidione |
|
|
Oxazidione is an anticoagulant compound and a useful pharmaceutical intermediate. |
|
T71532 |
Fondaparinux free base
|
|
|
|
Fondaparinux Free Base is a synthetic pentasaccharide that mediates the interaction of HEPARIN with ANTITHROMBINS and inhibits FACTOR Xa; it is used for prevention of VENOUS THROMBOEMBOLISM after surgery. Fondaparinux is... |
|
T19708 |
(S)-Warfarin
|
|
|
|
(S)-Warfarin is a more effective enantiomer of Warfarin. It is used as a vitamin K antagonist, with anticoagulant. |
|
T76561 |
Anpocogin
|
|
|
|
Anpocogin, a variant of the Ancyclostoma canium nematode anticoagulant protein c2 with an added C-terminal P85, is synthesized in Pichia pastoris and functions as an anticoagulant agent [1]. |
|
T23898 |
Clocoumarol
|
Clocoumarolum,BRN 1264788,DB 112 |
|
|
Clocoumarol is an anticoagulant that prevents blood clotting. It also can inhibit the dilatation of the spleen and the congestion of lymph nodes. |
|
T70184 |
YM-60828 dihydrochloride
|
|
|
|
YM-60828 dihydrochloride is a Factor Xa (FXa) inhibitor and anticoagulant used in the treatment of venous thromboembolic disease. |
|
TP1959 |
PM 102
|
|
|
|
Peptide that reverses the anticoagulant effect of heparin. Potently binds heparin (Kd = 36 nM in vitro). |
|
T30191 |
Atecegatran
|
metabolite of AZD0837,atecegatran metoxil |
|
|
Atecegatran is often used as an anticoagulant to treat cardiovascular disease. |
|
T80097 |
Hirullin P18
|
|
Thrombin
|
|
Hirullin P18 is a potent thrombin inhibitor with anticoagulant properties [1]. |
|
T39310 |
Sofigatran
|
MCC-977 |
|
|
Sofigatran (MCC-977) is an orally active inhibitor of factor IIa, also known as thrombin, and functions as an anticoagulant. It is primarily utilized in cardiovascular disease research. |
|
T71601 |
CU-2010
|
|
|
|
CU-2010 is a synthetic serine protease inhibitor with antifibrinolytic and anticoagulant properties. CU-2010 dose-dependently reduces postoperative blood loss and improves postischemic recovery after cardiac surgery in a... |
|
T62662 |
Tioclomarol
|
|
|
|
Tioclomarol is a coumarin anticoagulant and a vitamin K antagonist. |
|
TP1628 |
Activated Protein C (390-404), human
|
|
|
|
Activated Protein C (390-404), human, a peptide derived from the vitamin K-dependent serine protease, effectively suppresses the anticoagulant activity of APC[1]. |
