Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fluoxetine hydrochloride (Lilly110140) is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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25 mg | 在庫あり | ¥ 11,000 | |||
50 mg | 在庫あり | ¥ 15,000 | |||
100 mg | 在庫あり | ¥ 19,000 | |||
200 mg | 在庫あり | ¥ 34,000 | |||
500 mg | 在庫あり | ¥ 58,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 14,500 |
説明 | Fluoxetine hydrochloride (Lilly110140) is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants. |
In vitro | When co-administered in adult male SD rats, fluoxetine and olanzapine induce a robust and sustained increase in extracellular dopamine levels, with concentrations surpassing baseline by 361% and 272%, respectively—significantly higher than when either drug is used alone. Additionally, fluoxetine reverses the prolonged latency of escape caused by unavoidable shocks in adult male SD rats. |
In vivo | Fluoxetine accelerates the maturation of immature neurons. It enhances the proliferation of new cells in the dentate gyrus of the adult rat hippocampus, strengthens neurodependent long-term potentiation in the hippocampal dentate gyrus, and increases the number of proliferating cells in the prefrontal cortex. |
別名 | Fluoxetine HCl, LY-110140, Lilly110140 |
分子量 | 345.787 |
分子式 | C17H19ClF3NO |
CAS No. | 56296-78-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 3.5 mg/mL (10 mM)
DMSO: 34.6 mg/mL (100 mM)
You can also refer to dose conversion for different animals. 詳細
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Fluoxetine hydrochloride 56296-78-7 Autophagy GPCR/G Protein Neuroscience 5-HT Receptor Serotonin Transporter Fluoxetine HCl Fluoxetine SLC6A4 SERT inhibit Inhibitor LY 110140 5-HTT Fluoxetine Hydrochloride LY-110140 Lilly110140 LY110140 inhibitor