Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 : 0.07 μM),
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
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1 mg | 在庫あり | ¥ 28,000 | |||
5 mg | 在庫あり | ¥ 68,500 | |||
10 mg | 在庫あり | ¥ 106,500 | |||
25 mg | 在庫あり | ¥ 176,000 | |||
50 mg | 在庫あり | ¥ 245,500 | |||
100 mg | 在庫あり | ¥ 333,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 65,000 |
説明 | Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 : 0.07 μM), |
ターゲット&IC50 | CYP1A2 (human):0.07 µM |
In vitro | Furafylline was a potent, non-competitive inhibitor of high affinity phenacetin O-deethylase activity of microsomal fractions of human liver, a reaction catalysed by P450IA2, with an IC50 value of 0.07 microM[1]. |
In vivo | Furafylline was originally introduced as a bronchodilator with extended duration compared to theophylline[1]. |
分子量 | 260.25 |
分子式 | C12H12N4O3 |
CAS No. | 80288-49-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12.5 mg/mL (48.03 mM)
You can also refer to dose conversion for different animals. 詳細
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Furafylline 80288-49-9 Metabolism P450 Cytochrome P450 inhibit Inhibitor CYPs inhibitor