keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
G3335 Acetate was discovered to be a novel PPARgamma antagonist.
説明 | G3335 Acetate was discovered to be a novel PPARgamma antagonist. |
ターゲット&IC50 | PPARγ:8.34 μM(kd), PPARγ:8.67 μM(kd) |
In vitro | G3335 exhibits a highly specific binding affinity against PPARgamma (K(D) = 8.34 microM) and is able to block rosiglitazone, a potent PPARgamma agonist, in the stimulation of the interaction between the PPARgamma ligand-binding domain (LBD) and RXRalpha-LBD. Yeast two-hybrid assays demonstrated that G3335 exhibits strong antagonistic activity (IC50 = 8.67 microM) in perturbing rosiglitazone in the promotion of the PPARgamma-LBD-CBP interaction. |
別名 | G3335 Acetate (36099-95-3 free base) |
分子量 | 393.39 |
分子式 | C18H23N3O7 |
CAS No. | T21598L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (139.81 mM)
You can also refer to dose conversion for different animals. 詳細
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G3335 Acetate T21598L DNA Damage/DNA Repair Metabolism PPAR 36099-95-3 36099-95-3 free base G3335 Acetate (36099-95-3 free base) G 3335 Acetate G-3335 Acetate Inhibitor inhibitor inhibit