Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 16,000 | |||
5 mg | 在庫あり | ¥ 34,500 | |||
10 mg | 在庫あり | ¥ 53,000 | |||
25 mg | 在庫あり | ¥ 98,000 | |||
50 mg | 在庫あり | ¥ 145,000 | |||
100 mg | 在庫あり | ¥ 202,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 29,000 |
説明 | GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively. |
ターゲット&IC50 | RIP1 (monkey):20 nM, RIP1 (human):16 nM |
In vitro | GSK2982772 ?potently binds to RIP1 with exquisite kinase specificity and has excellent activity in blocking many TNF-dependent cellular responses.?Highlighting its potential as a novel anti-inflammatory agent, the inhibitor was also able to reduce spontaneous production of cytokines from human ulcerative colitis explants. |
分子量 | 377.4 |
分子式 | C20H19N5O3 |
CAS No. | 1622848-92-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (264.97 mM)
You can also refer to dose conversion for different animals. 詳細
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GSK2982772 1622848-92-3 Apoptosis NF-Κb RIP kinase inhibit Receptor-interacting protein kinases RIPK Inhibitor GSK-2982772 GSK 2982772 inhibitor