Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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50 mg | 在庫あり | ¥ 9,500 | |||
100 mg | 在庫あり | ¥ 13,500 | |||
500 mg | 在庫あり | ¥ 18,000 | |||
1 g | 在庫あり | ¥ 21,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Ganciclovir sodium (Cytovene IV sodium) is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1). |
ターゲット&IC50 | FHV-1:5.2 μM |
In vitro | Ganciclovir showed activity against feline herpesvirus type-1 (FHV-1, IC50 = 5.2 microM)[1]. |
In vivo | In adult rats, the intracochlear diffusion of ganciclovir was shown to achieve the same concentration as in blood. In gestating mice, transplacental diffusion was observed, with a fetal-to-maternal blood ratio of 0.5. In newborn mice, the plasma concentration profile of ganciclovir showed a peak at 2 h followed by a gradual decrease. In adult mice, the concentration peaked at 1 h, but became undetectable by 2 h after injection. Counts of white blood cells, red blood cells and platelets decreased significantly in ganciclovir-treated newborn mice[3]. |
別名 | RS-21592 sodium, Cytovene IV sodium, 2'-Nor-2'-deoxyguanosine sodium, BW 759 sodium |
分子量 | 278.22 |
分子式 | C9H13N5NaO4 |
CAS No. | 107910-75-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 40 mg/mL (144.29 mM)
DMSO: 3.06 mg/mL (10.98 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Ganciclovir sodium 107910-75-8 Cell Cycle/Checkpoint DNA Damage/DNA Repair Microbiology/Virology Others Nucleoside Antimetabolite/Analog Antifection HSV group orally active BW759 inhibit polymerase CNS penetration DNA serotype BW 759 RS-21592 sodium Herpes simplex virus Antibiotic replication Cytovene IV sodium 2'-Nor-2'-deoxyguanosine sodium BW 759 sodium herpes Ganciclovir BW-759 infection Inhibitor viruse CMV Cytomegalovirus inhibitor