Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hamaudol is a chromone isolated from Saposhnikovia divaricata,has analgesic and anti-inflammary activities, it showed inhibitory activity on COX-1 and COX-2 activities with values of 0.30, 0.57 mM, respectively.
説明 | Hamaudol is a chromone isolated from Saposhnikovia divaricata,has analgesic and anti-inflammary activities, it showed inhibitory activity on COX-1 and COX-2 activities with values of 0.30, 0.57 mM, respectively. |
ターゲット&IC50 | COX-2:57 mM , COX-1:0.30 mM |
In vitro | The CHCl3 extract of the root of Angelica japonica showed high inhibitory activity against human gastric adenocarcinoma (MK-1) cell growth. From this extract, a new furanocoumarin named japoangelone and four furanocoumarin ethers of falcarindiol, named japoangelols A-D, were isolated together with caffeic acid methyl ester, four polyacetylenic compounds (panaxynol, falcarindiol, 8-O-acetylfalcarindiol, and (9Z)-1,9-heptadecadiene-4,6-diyne-3,8,11-triol), eight coumarins (osthol, isoimperatorin, scopoletin, byakangelicin, xanthotoxin, bergapten, oxypeucedanin methanolate, and oxypeucedanin hydrate), and two chromones (3'-O-acetylHamaudol, and Hamaudol)[1] |
植物由来 |
分子量 | 276.28 |
分子式 | C15H16O5 |
CAS No. | 735-46-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: <10mM
You can also refer to dose conversion for different animals. 詳細
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Hamaudol 735-46-6 Immunology/Inflammation Neuroscience COX Inhibitor Cyclooxygenase inhibit inhibitor