store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quiescent state of non-injured hepatic stem cells and thus rescues liver failure. Hh-Ag1.5 induced differentiation of hiPSCs into skin precursor cells, spinal motor neurons and spinal sensory neurons.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 36,500 | |||
5 mg | 在庫あり | ¥ 91,500 | |||
10 mg | 在庫あり | ¥ 144,500 | |||
25 mg | 在庫あり | ¥ 225,500 | |||
50 mg | 在庫あり | ¥ 310,000 | |||
100 mg | 在庫あり | ¥ 418,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 100,500 |
説明 | Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quiescent state of non-injured hepatic stem cells and thus rescues liver failure. Hh-Ag1.5 induced differentiation of hiPSCs into skin precursor cells, spinal motor neurons and spinal sensory neurons. |
ターゲット&IC50 | Hedgehog:1 nM (EC50) |
別名 | SAG-1.5, SAG1.5, SAG 1.5 |
分子量 | 526.04 |
分子式 | C28H26ClF2N3OS |
CAS No. | 612542-14-0 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 26.30 mg/mL (50 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Hh-Ag1.5 612542-14-0 GPCR/G Protein Stem Cells Hedgehog/Smoothened SAG-1.5 SAG1.5 HhAg1.5 Hh-Ag-1.5 Hh Ag1.5 SAG 1.5 Inhibitor inhibitor inhibit