Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC50 = 1 nM) and PBMCs (IC50 = 9 nM).
ターゲット&IC50 | HIV-1 (NL4.3 strain):1 nM (in MT-4 cells), HIV-1 (NL4.3 strain):3 nM (in MT-4 cells), HIV-1 (NL4.3 strain):9 nM (in PBMCs), [125I]-SDF-CXCR4:13 nM |
別名 | AMD-070 |
分子量 | 349.47 |
分子式 | C21H27N5 |
CAS No. | 558447-26-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 44 mg/mL (125.9 mM)
H2O: 7 mg/mL (20.03 mM), Heating is recommended.
DMSO: 17 mg/mL (48.64 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Mavorixafor 558447-26-0 Autophagy GPCR/G Protein Immunology/Inflammation CXCR Human immunodeficiency virus AMD070 HIV AMD-070 inhibit CXC chemokine receptors AMD 070 Inhibitor inhibitor