Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
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1 mg | 在庫あり | ¥ 8,000 | |||
2 mg | 在庫あり | ¥ 11,000 | |||
5 mg | 在庫あり | ¥ 18,000 | |||
10 mg | 在庫あり | ¥ 29,000 | |||
25 mg | 在庫あり | ¥ 58,500 | |||
50 mg | 在庫あり | ¥ 98,500 | |||
100 mg | 在庫あり | ¥ 147,000 |
説明 | MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor. |
In vitro | MAZ51 is able to block the proliferation of VEGFR-3-expressing human endothelial cells and is less potently able to induce their apoptosis.?MAZ51 also inhibits the proliferation and induces the apoptosis of a variety of non-VEGFR-3-expressing tumor cell lines[1]. |
In vivo | In vivo, MAZ51 significantly inhibits the growth of rat mammary carcinomas.?These data establish MAZ51 as a compound with antitumor properties that inhibits tumor growth directly and also indirectly by interfering with tumor-host interactions[1]. |
分子量 | 314.38 |
分子式 | C21H18N2O |
CAS No. | 163655-37-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.33 mg/mL(10.59 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MAZ51 163655-37-6 Angiogenesis Apoptosis Tyrosine Kinase/Adaptors VEGFR EGFR growth phosphorylation Inhibitor inhibit PDGFRβ MAZ 51 tumor VEGF-D indolinone MAZ-51 IGF-1R VEGF-C Vascular endothelial growth factor receptor ligand-induced proliferation inhibitor