| T0965 |
Histamine
|
Ergamine |
5-HT Receptor
,
Endogenous Metabolite
,
Histamine Receptor
|
|
Histamine (Ergamine) is an amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting ne... |
| T6534 |
Histamine dihydrochloride
|
peremin,Ceplene,Histamine 2HCl |
Endogenous Metabolite
,
Histamine Receptor
|
|
Histamine dihydrochloride (Ceplene) is dihydrochloride form of Histamine. Histamine is an organic nitrogen compound which is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodila... |
| T6535 |
Histamine Phosphate
|
Histamine diphosphate,Histamine acid phosphate |
Histamine Receptor
|
|
Histamine Phosphate (Histamine acid phosphate) acts directly on the blood vessels to dilate arteries and capillaries mediated by both H 1- and H 2-receptors. |
| T20712 |
Conessine
|
Conessinum,Wrightine,Roquessine,Neriine,Konessin |
Histamine Receptor
|
|
Conessine (Conessinum), a steroidal alkaloid isolated from Holarrhena floribunda, interacts with the histamine H3 receptor and has anti-malarial activity. |
| T20884 |
Hydroxyzine
|
Hydroxyzine free base |
Histamine Receptor
|
|
Hydroxyzine (Hydroxyzine free base) is an antagonist of histamine H1-receptor. |
| T4940 |
3-Methylhistamine dihydrochloride
|
|
Others
,
Endogenous Metabolite
|
|
N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histamine metabolite is generally less hampere... |
| TN6737 |
(25R)-Spirost-4-ene-3,12-dione
|
|
Others
|
|
(25R)-Spirost-4-ene-3,12-dione is a natural product. |
| T19443 |
N-Acetylhistamine
|
N-Omega-acetylhistamine |
Endogenous Metabolite
,
Histamine Receptor
|
|
N-Acetylhistamine (N-Omega-acetylhistamine) is a metabolite of histamine. |
| T0330 |
Diphenhydramine hydrochloride
|
Diphenhydramine HCl,DPH |
Histamine Receptor
|
|
Diphenhydramine hydrochloride (DPH) is a histamine H1 antagonist used as an antitussive and antiemetic. It is also used for pruritus and dermatoses, for hypersensitivity reactions, as an antiparkinson, a hypnotic, and as... |
| TN1008 |
Psoralenoside
|
|
CaMK
,
Calcium Channel
,
Histamine Receptor
|
|
Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity. |
| T2520 |
Desloratadine
|
Sch34117,NSC 675447 |
Endogenous Metabolite
,
Histamine Receptor
|
|
Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smoot... |
| T2848 |
Osthole
|
Osthol,NSC 31868,Ostol |
Apoptosis
,
HBV
,
Parasite
,
Histamine Receptor
|
|
Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation. |
| T0783 |
Mianserin hydrochloride
|
Mianserin HCl,Org GB 94,ORG GB-94 HCl |
Dopamine Receptor
,
5-HT Receptor
,
Opioid Receptor
,
Adrenergic Receptor
,
Histamine Receptor
|
|
Mianserin hydrochloride (Org GB 94) is a tetracyclic compound with antidepressant effects. it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors. It may cause drowsiness and hematolog... |
| T20597 |
Alginic acid
|
Protanal LF,Snow acid algin G,Kelacid,Sazzio,Norgine |
Apoptosis
,
Autophagy
,
Histamine Receptor
|
|
Alginic acid (Snow acid algin G) is a natural polysaccharide extracted from brown seaweeds with anti-anaphylactic and anti-inflammatory activities. Alginic acid inhibits histamine release and can be used in the food indu... |
| T8790 |
1-Methylhistamine dihydrochloride
|
|
Endogenous Metabolite
|
|
1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains... |
| T13487 |
1-Methylhistamine
|
2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine |
Others
|
|
2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine is a histamine metabolite. |
| T19443L |
N-Acetylhistamine acetate
|
|
Endogenous Metabolite
,
Histamine Receptor
|
|
N-Acetylhistamine acetate is a histamine metabolite. It can be used as a potential biomarker of histidine metabolism for anaphylactoid reactions. |
| T4899 |
L-Histidinol dihydrochloride
|
|
Endogenous Metabolite
|
|
L-Histidinol dihydrochloride is a precursor of histamine and a reversible inhibitor of protein synthesis. |
| T0927 |
Butylparaben
|
Butyl 4-hydroxybenzoate,Butyl parahydroxybenzoate |
Endogenous Metabolite
,
Antibacterial
,
Antibiotic
|
|
Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity. |
| T5S1286 |
(+)-Columbianetin
|
(S)-Columbianetin,Columbianetin |
Antifungal
|
|
(+)-Columbianetin ((S)-Columbianetin) is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. (+)-Columbianetin has anti-inflammatory effect... |
| T1297 |
Eugenol
|
4-Allylguaiacol,Allylguaiacol,4-Allyl-2-methoxyphenol,Eugenic acid |
Apoptosis
,
Ferroptosis
,
Reactive Oxygen Species
,
Antibacterial
,
Parasite
|
|
Eugenol (Allylguaiacol) is a Standardized Chemical Allergen. The physiologic effect of eugenol is by means of Increased Histamine Release and Cell-mediated Immunity. |
| T0908 |
Chlorquinaldol
|
5,7-Dichloro-8-hydroxy-2-methylquinoline,Chloquinan |
Antibacterial
,
Antibiotic
,
Antifungal
|
|
Chlorquinaldol (5,7-Dichloro-8-hydroxy-2-methylquinoline) is a Standardized Chemical Allergen. The physiologic effect of chlorquinaldol is by means of Increased Histamine Release, and Cell-mediated Immunity. |
| T3429 |
Protopine
|
Macleyine,Hypercorine,Corydinine,Biflorine,Fumarine |
Reactive Oxygen Species
,
Platelet aggregation
,
Histamine Receptor
|
|
Protopine (Fumarine) is a benzylisoquinoline alkaloid. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic. |
| T0834 |
Ethylparaben
|
Ethyl 4-hydroxybenzoate,Ethyl parahydroxybenzoate |
Antibacterial
,
Antifungal
|
|
Ethylparaben (Ethyl parahydroxybenzoate) is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. |
| TN1154 |
Nepetin
|
6-Methoxyluteolin |
Calcium Channel
,
Histamine Receptor
|
|
Nepetin (6-Methoxyluteolin) has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. |
| TN1661 |
Ganoderic acid C2
|
|
Reductase
,
Histamine Receptor
,
Immunology/Inflammation related
|
|
Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen. |
| T2A2532 |
L-Histidine
|
Glyoxaline-5-alanine,L-(-)-Histidine,histidine,L-Hisidine |
Mitochondrial Metabolism
,
Endogenous Metabolite
|
|
L-Histidine (L-(-)-Histidine) is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, L-Histidine is important for maintenance of myelin sheaths that protect ne... |
| T5S1889 |
Yunaconitine
|
Guayewuanine B |
Others
|
|
1. Yunaconitine (Guayewuanine B) has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg/kg. 3. Yunaconitine shows po... |
| T3728 |
Methyl Paraben
|
Methyl parahydroxybenzoate,Nipagin,Methylparaben,Methyl 4-hydroxybenzoate,Methyl p-hydroxybenzoate |
Endogenous Metabolite
,
Antibacterial
,
Antibiotic
|
|
The physiologic effect of Methyl Paraben (Nipagin) is by means of Increased Histamine Release, and Cell-mediated Immunity. Methyl Paraben (Nipagin) is an antimicrobial agent, preservative, flavouring agent. Methyl Parabe... |
| TN3483 |
Bakkenolide D
|
|
IL Receptor
,
Histamine Receptor
|
|
Bakkenolide D has anti-allergic effect, it and bakkenolide D demonstrates inhibitory effect on the trachea contraction induced by histamine in vitro, they have obvious anti-histamine activities. |
| TN5279 |
Zeorin
|
|
ATPase
,
Calcium Channel
,
Antifection
,
Histamine Receptor
|
|
Zeorin shows strong inhibition activity against bacteria and fungi. It markedly exhibits inhibitory activity on histamine release from mast cell induced by DNP24-BSA, it shows potent inhibitory effect by 40% decrease of ... |
| TN2155 |
Rhodiocyanoside A
|
|
Histamine Receptor
|
|
Rhodiocyanoside A has antiallergic activity, it exhibits inhibitory activity on the histamine release from rat peritoneal exudate cells sensitized with anti-DNP IgE and inhibits the PCA reaction in rats. |
| TN3699 |
Corchoionoside C
|
|
Antifection
,
Histamine Receptor
|
|
Corchoionoside C has antioxidant activity, shows strong scavenging activities on DPPH radical, it also shows weak antifungal activity. Corchoionosides A, B, and C inhibit the histamine release from rat peritoneal exudate... |
| TN5647 |
Confluentin
|
|
|
|
Confluentin has antimicrobial activity against the gram-positive bacteria.Confluentin significantly inhibits compound 48/80-induced histamine release from rat peritoneal mast cells. Confluentin also shows weak cytotoxici... |
| TN4392 |
Koaburaside
|
|
IL Receptor
,
TNF
,
Influenza Virus
|
|
Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have anti-allergic inflammatory activity, it can suppress histam... |
| TMA0627 |
Taxiresinol
|
|
TNF
|
|
Taxiresinol shows anticancer, antinociceptive, and antiallergic activities, it shows inhibitory activity on induced histamine release from the human basophilic cell line, KU812. Taxiresinol can protect the hepatocytes fr... |
| TN1913 |
Marmin
|
|
Calcium Channel
,
Antifection
,
Histamine Receptor
|
|
Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the prevention of the effects of endogenous... |
| TN3325 |
9-O-Feruloyl-5,5'-dimethoxylariciresinol
|
|
IL Receptor
,
TNF
|
|
(+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol may have anti-allergic inflammatory effect, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell lines, ... |
| T80998 |
Thapsigargicin
|
Thapsigargicine |
|
|
Thapsigargicin (Thapsigargicine) acts as an activator for mast cells and leukocytes, prompting histamine release from rat peritoneal mast cells and human basophil leukocytes. Additionally, it elevates cytoplasmic free ca... |
