Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).
説明 | NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM). |
ターゲット&IC50 | D5:> 10000 nM(Ki), D1:> 10000 nM(Ki), 5-HT2:223 nM(Ki), α1-adrenoceptor:642 nM(Ki), D4:> 5000 nM(Ki), D3:1.4 nM(Ki), D2:217 nM(Ki) |
別名 | NGB2904 HCl, NGB-2904, NGB2904 |
分子量 | 494.46 |
分子式 | C28H29Cl2N3O |
CAS No. | 189060-98-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 16.25 mg/ml (30.61 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
NGB 2904 189060-98-8 GPCR/G Protein Neuroscience Others 5-HT Receptor Dopamine Receptor addiction NGB2904 HCl orally NGB-2904 active cocaine NGB2904 dopamine inhibit Inhibitor selective inhibitor