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カタログ番号	製品名	別名	ターゲット
T8348	Phentolamine		Adrenergic Receptor
	Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist		Adrenergic Receptor
T35862	Cucurbit[8]uril		Others
	Cucurbit[8]uril is a highly effective and safe supramolecular compound that promotes protein heterodimerization. It selectively induces the heterodimerization of methylviologen and naphthalene functionalized proteins, de...		Others
T8345	Carbutamide		Others
	Carbutamide is a sulfonylurea antidiabetic agent with hypoglycemic activity.		Others
T8580	Bupranolol		Adrenergic Receptor
	Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.		Adrenergic Receptor
T9565	OSBPL7-IN-1		Others
	OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1].		Others
T9692	Paltusotine		Somatostatin
	Paltusotine is a nonpeptide, small molecule somatostatin type 2 (SST2) receptor agonist with high oral bioavailability. Paltusotine maintains GH and IGF-1 levels in acromegaly patients		Somatostatin
T1292	Tiapride hydrochloride		Dopamine Receptor
	Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdraw...		Dopamine Receptor
T9732	VY-3-135		Fatty Acid Synthase
	VY-3-135 is a metastasis inhibitor and an acetyl-CoA synthetase 2 (ACSS2) modulator.		Fatty Acid Synthase
T8734	Choline		Others
	Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins		Others
T34896	Tofisopam	Emandaxin,Grandaxin	Others
	Tofisopam (Grandaxin) is a 2,3-benzodiazepine compound with anxiolytic activity that can be taken orally.		Others
T15500	HPi1		Others , Antibacterial
	HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri...		Others , Antibacterial
T9346	CVN424		GPR
	CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.		GPR
T16115	MLi-2		LRRK2
	MLi-2 is a structurally novel, highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a ce...		LRRK2
T3306	PF-04418948	PF 04418948,PF04418948	Prostaglandin Receptor
	PF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a divers...		Prostaglandin Receptor
T9214	ELOVL6-IN-1		Others
	ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner...		Others
T9683	VX-150		Sodium Channel
	VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).		Sodium Channel
T9215	ELOVL6-IN-2		Others
	ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.		Others
T2013	Ponalrestat		Reductase
	Ponalrestat is an aldose reductase inhibitor.		Reductase
T39695	ARD-2128		Androgen Receptor
	ARD-2128 is a highly potent, orally bioavailable PROTAC (proteolysis-targeting chimera) degrader of the androgen receptor (AR), effectively diminishing AR protein levels, suppressing AR-regulated gene expression in tumor...		Androgen Receptor
T6710	Troxipide	Aplace	Others
	Troxipide (Aplace), a new-type systemic non-antisecretory gastric cytoprotective agent, which is mucus-secreting, anti-ulcer, and anti-inflammatory properties irrespective of pH of stomach or duodenum.		Others
T9805	BAY 2666605		PDE
	BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.		PDE
T9164	BMS-986242	BMS986242	IDO , Indoleamine 2,3-Dioxygenase (IDO)
	BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T21740	RD162		Androgen Receptor
	RD162 is a non-steroidal antiandrogen (NSAA) specifically binding to the androgen receptor (AR).		Androgen Receptor
T3713	BAY-876		transporter
	BAY-876 is an orally active and selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM). BAY-876 exhibits >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 also inhibits glycolytic metabol...		transporter
T38776	LP-922056		Wnt/beta-catenin
	LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.		Wnt/beta-catenin
T9590	T-1095		SGLT , transporter
	T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).		SGLT , transporter
T2436	GSK2801		Apoptosis , Epigenetic Reader Domain
	GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.		Apoptosis , Epigenetic Reader Domain
T10096L	Voruciclib		CDK
	Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM). Voruciclib represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma. Voruciclib effectively blocks CDK9, the ...		CDK
T13186	TL02-59		Apoptosis , Src , Hck
			Apoptosis , Src , Hck
T2629	UNC2881		TAM Receptor
	UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.		TAM Receptor
T9977	SGK1-IN-4		SGK
	SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.		SGK
T11339	Furegrelate sodium	U-63557A	PPAR
			PPAR
T40548	NH-3		Thyroid hormone receptor(THR)
	NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the...		Thyroid hormone receptor(THR)
T8432	ASP4132		AMPK
	ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.		AMPK
T12401	Pemigatinib	INCB054828	FGFR
	Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).		FGFR
T12266	Ilginatinib	NS-018	Tyrosine Kinases , JAK
	Ilginatinib (NS-018) is a highly active and orally bioavailable inhibitor of JAK2.		Tyrosine Kinases , JAK
T15656	KGA-2727		SGLT
	KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA...		SGLT
T7686	Ramiprilat		RAAS
	Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.		RAAS
T5347	CXD101	CXD-101	HDAC
	CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II		HDAC
T5491	GSK3179106		c-RET
	GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM		c-RET
T25492	Hepln-13	Hepln 13,Hepln13	c-Met/HGFR
	Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.		c-Met/HGFR
T12979	BI-3406		p38 MAPK , MAPK , Ras
	BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.		p38 MAPK , MAPK , Ras
T8322	BL-918		Autophagy
	BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.		Autophagy
T10525	SCD1 inhibitor-4		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T8581	Flecainide hydrochloride		Others
	Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.		Others
T4061	LY2334737		Nucleoside Antimetabolite/Analog , Others , Virus Protease
	LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.		Nucleoside Antimetabolite/Analog , Others , Virus Protease
T9043	AS1810722		P450 , STAT
	AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a promising candidate f...		P450 , STAT
T11399	Giredestrant	GDC-9545	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Giredestrant (GDC-9545) potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand,...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T9575	MRTX9768		Histone Methyltransferase
	MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.		Histone Methyltransferase
T21712	BAY 41-8543		Others , Guanylate cyclase
	BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).		Others , Guanylate cyclase

Compounds

Phentolamine

T8348

Synonym:

Target: Adrenergic Receptor

Target: Adrenergic Receptor

Tiapride hydrochloride

T1292

Synonym:

Target: Dopamine Receptor

VY-3-135

T9732

Synonym:

Target: Fatty Acid Synthase

Synonym: Emandaxin,Grandaxin

Target: Others, Antibacterial

Synonym: PF 04418948,PF04418948

Target: Prostaglandin Receptor

Target: Sodium Channel

Target: Androgen Receptor

Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)

RD162

T21740

Synonym:

Target: Androgen Receptor

Target: Wnt/beta-catenin

T-1095

T9590

Synonym:

Target: SGLT, transporter

GSK2801

T2436

Synonym:

Target: Apoptosis, Epigenetic Reader Domain

Target: Apoptosis, Src, Hck

Target: Thyroid hormone receptor(THR)

Target: Tyrosine Kinases, JAK

Synonym: Hepln 13,Hepln13

Target: p38 MAPK, MAPK, Ras

Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

Flecainide hydrochloride

Target: Nucleoside Antimetabolite/Analog, Others, Virus Protease

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

MRTX9768

T9575

Synonym:

Target: Histone Methyltransferase

BAY 41-8543

T21712

Synonym:

Target: Others, Guanylate cyclase

カタログ番号	製品名	別名	ターゲット
TN2081	Maohuoside A		MAPK
	Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.		MAPK
T13795	Nicotinamide riboside		Sirtuin
	Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.		Sirtuin
T40615	N,N'-Dimethylthiourea	DMTU	Antioxidant
	N,N'-Dimethylthiourea (DMTU) (DMTU), isolated from Allii Sativi Bulbus, is an orally active scavenger of hydroxyl radical ( OH) and blocks OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects a...		Antioxidant
T3858	Macranthoidin A		Others
	Macranthoidin A has anti-inflammation activity.		Others
T4S1114	Dryocrassin ABBA	Dryocrassin	Influenza Virus , Antibacterial
	Dryocrassin ABBA (Dryocrassin) is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities.		Influenza Virus , Antibacterial
T5S1895	Norisoboldine	Laurelliptine,(+)-Laurelliptine	MAPK , Adenosine Receptor
	1. Norisoboldine ((+)-Laurelliptine) might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. 2. Norisobo...		MAPK , Adenosine Receptor
TN2423	Safranal		Antioxidant
	Safranal is the special volatile aroma compound of saffron		Antioxidant
T1560	Prednisolone	Predonine,Hydroretrocortine,Metacortandralone	Glucocorticoid Receptor , Endogenous Metabolite
	Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.		Glucocorticoid Receptor , Endogenous Metabolite
T0848	L-DOPA	Levodopa,3,4-Dihydroxyphenylalanine	Dopamine Receptor , Endogenous Metabolite
	L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai...		Dopamine Receptor , Endogenous Metabolite
T5784	Topotecan	NSC 609669,SKF 104864A	Topoisomerase , Autophagy
	Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.		Topoisomerase , Autophagy
T1611	Isotretinoin	13-cis-Retinoic acid	Retinoid Receptor , Endogenous Metabolite , Autophagy
	Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall...		Retinoid Receptor , Endogenous Metabolite , Autophagy
T6220	Nicotinamide riboside chloride		Sirtuin , Endogenous Metabolite
	Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.		Sirtuin , Endogenous Metabolite
T6368	Abscisic Acid	Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin）	Others , Proton pump , Endogenous Metabolite
	Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.		Others , Proton pump , Endogenous Metabolite
T1326	Gentamicin sulfate	SCH9724,Gentamycin sulfate,NSC-82261	ribosome , DHFR , Antibacterial , Antibiotic
	Gentamicin sulfate (SCH9724) is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms.		ribosome , DHFR , Antibacterial , Antibiotic
T0974	Novobiocin Sodium	Albamycinsodium,Cathomycin,Albamycin	Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy
	Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim...
T5283	NADH disodium salt	Disodium NADH,NADH, disodium salt hydrate	Others , Endogenous Metabolite
	NADH disodium salt (Disodium NADH) hydrate is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH disodium salt hydrate becomes oxid...		Others , Endogenous Metabolite
T7727	Se-Methylselenocysteine	Se MSC,SeMCys,MSeC,Se-MSC,SeMSC	BCL , IAP , Caspase
	Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.		BCL , IAP , Caspase
T6194	Fidaxomicin	Tiacumicin B,OPT-80,Clostomicin B1,PAR-101	Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic
	Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme el...		Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic
T2719	Succinic acid	Asuccin,Amber acid,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid	Endogenous Metabolite
	Succinic acid (1,2-Ethanedicarboxylic acid) is a water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is al...		Endogenous Metabolite
T3417	Amentoflavone	Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin	Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal
	Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib...
T2755	Rhoifolin	Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside	Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
	Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
T6460	Cysteamine hydrochloride	2-Mercaptoethylamine Hydrochloride,β-Mercaptoethylamine Hydrochloride,Thioethanolamine Hydrochloride,2-Aminoethanethiol Hydrochloride,Cysteamine HCl,Bekaptan	Apoptosis , Others , Reactive Oxygen Species , Endogenous Metabolite , Autophagy
	Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.
T2807	Caffeic Acid		Lipoxygenase , Endogenous Metabolite , TRP/TRPV Channel
	Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities.		Lipoxygenase , Endogenous Metabolite , TRP/TRPV Channel
T2933	Wogonin	Vogonin	Apoptosis , Wnt/beta-catenin , CDK , Autophagy
	Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.		Apoptosis , Wnt/beta-catenin , CDK , Autophagy
T13092	Tauro-Obeticholic acid		FXR
	Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).		FXR
T1424	Ethynyl estradiol	17α-Ethynylestradiol,Ethinyl Estradiol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
	Ethynyl estradiol is a semisynthetic alkylated ESTRADIOL with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in ORAL CONTRACEPTIVES...
TQ0288	Hexahydrocurcumin		Reactive Oxygen Species , ROS , COX
	Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.		Reactive Oxygen Species , ROS , COX
T5041	Faropenem sodium		Antibacterial , Antibiotic
	Faropenem sodium is an orally bioavailable penem antibiotic which can efficiently kill Mycobacterium tuberculosis.It treatment of tuberculosis and community-acquired pneumonia.		Antibacterial , Antibiotic
T3912	Saikosaponin B1		Others
	Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.		Others
T4912	Jatrorrhizine chloride	Yatrorhizine chloride,Neprotine chloride	Others , 5-HT Receptor , OCT , Antibacterial , AChE
	Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h...		Others , 5-HT Receptor , OCT , Antibacterial , AChE
TN2429	Capsiate		Antioxidant , TRP/TRPV Channel
	Capsiate is an orally active TRPV1 agonist, a non-irritating capsaicin analog that acts as an antiallergic agent with anti-inflammatory, antioxidant, hypoglycemic, and inhibitory angiogenic activity.		Antioxidant , TRP/TRPV Channel
T2947	Indole-3-carbinol	I3C,3-Indolemethanol,Indole-3-Methanol	E1/E2/E3 Enzyme , NF-κB , Aryl Hydrocarbon Receptor , Endogenous Metabolite , p53
	Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activation.
T7064	Valproic Acid	Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid	Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy
	Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research.
T1261	Medroxyprogesterone Acetate	Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,Farlutin,Medroxyprogesterone (acetate)	Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , Androgen Receptor , Endogenous Metabolite
	Medroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been...
T1126	Penicillin V Potassium	Penicillin V potassium salt,Phenoxymethylpenicillin potassium salt	Antibacterial , Antibiotic
	Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is a broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.		Antibacterial , Antibiotic
T0948L	Corticosterone	17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)	Glucocorticoid Receptor , Endogenous Metabolite
	Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stres...		Glucocorticoid Receptor , Endogenous Metabolite
T11060	DMAPT	Dimethylamino Parthenolide	NF-κB
	DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells.		NF-κB
T3S2007	MRE-269	MRE 269,ACT-333679,MRE269	Prostaglandin Receptor
	MRE-269 (ACT-333679) is an orally available and long-acting prostacyclin receptor agonist prodrug. MRE-269(ACT-333679) is used for the treatment of pulmonary arterial hypertension. MRE-269(ACT-333679) is an active metabo...		Prostaglandin Receptor
T1670	Lanatoside C	Cedilanid,Ceglunate,Isolanid	ATPase , Virus Protease , Autophagy
	Lanatoside C (Ceglunate) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Lanatoside C can be used orally or by the intrav...		ATPase , Virus Protease , Autophagy
TJS2216	Aurantiamide acetate	Asperglaucide	Cysteine Protease
	Aurantiamide acetate (Asperglaucide) was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selective and orally active cathepsin inhibitor. Aurantiamide aceta...		Cysteine Protease
T13506	3β-Ursodeoxycholic acid	Isoursodeoxycholic acid
	3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) is a bile acid. 3β-Ursodeoxycholic acid (administered orally has shown good tolerability and good intestinal absorption. 3β-Ursodeoxycholic acid can undergo enzymatic iso...
T16442	PCO371	2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-	Thyroid hormone receptor(THR)
	PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormon...		Thyroid hormone receptor(THR)
T0461	Berberine chloride	Berberine hydrochloride,Benzodioxide,Natural Yellow 18	Reactive Oxygen Species , Topoisomerase , Antibacterial , Antibiotic , Autophagy
	Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally but has been used orally for various fungal an...
T37152	3-Methyl-2-cyclopenten-1-one		Endogenous Metabolite
	3-Methyl-2-cyclopenten-1-one can be used as a food additive to improve the flavor of meat and meat products at 2-5 ppm. Addition of 3-Methyl-2-cyclopenten-1-one showed gastric cytoprotective activity when administered or...		Endogenous Metabolite
T0883	Tramiprosate	Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed	Beta Amyloid , GABA Receptor
	Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GAB...		Beta Amyloid , GABA Receptor
T20643	Cefoxitin	Rephoxitin,Cefoxitinum	Cell wall , Antibacterial , Antibiotic
			Cell wall , Antibacterial , Antibiotic
T5S1889	Yunaconitine	Guayewuanine B	Others
	1. Yunaconitine (Guayewuanine B) has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg/kg. 3. Yunaconitine shows po...		Others
T15248	Estetrol	Donesta	Estrogen Receptor/ERR , Endogenous Metabolite
	Estetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.Estetrol has effects on the endometrium or cent...		Estrogen Receptor/ERR , Endogenous Metabolite
T2220	2-Methoxyestradiol	NSC-659853,2-MeOE2,2-ME2	Apoptosis , Reactive Oxygen Species , Microtubule Associated , Endogenous Metabolite , HIF , Autophagy
	2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endotheli...
T6491	(-)-(S)-Equol	(−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective a...
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天然物製品

Nicotinamide riboside

T13795

Synonym:

Target: Sirtuin

N,N'-Dimethylthiourea

Target: Influenza Virus, Antibacterial

Norisoboldine

T5S1895

Synonym: Laurelliptine,(+)-Laurelliptine

Target: MAPK, Adenosine Receptor

Synonym: Predonine,Hydroretrocortine,Metacortandralone

Target: Glucocorticoid Receptor, Endogenous Metabolite

L-DOPA

T0848

Synonym: Levodopa,3,4-Dihydroxyphenylalanine

Target: Dopamine Receptor, Endogenous Metabolite

Topotecan

T5784

Synonym: NSC 609669,SKF 104864A

Target: Topoisomerase, Autophagy

Isotretinoin

T1611

Synonym: 13-cis-Retinoic acid

Target: Retinoid Receptor, Endogenous Metabolite, Autophagy

Nicotinamide riboside chloride

T6220

Synonym:

Target: Sirtuin, Endogenous Metabolite

Abscisic Acid

T6368

Synonym: Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin）

Target: Others, Proton pump, Endogenous Metabolite

Gentamicin sulfate

T1326

Synonym: SCH9724,Gentamycin sulfate,NSC-82261

Target: ribosome, DHFR, Antibacterial, Antibiotic

Novobiocin Sodium

T0974

Synonym: Albamycinsodium,Cathomycin,Albamycin

Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy

NADH disodium salt

T5283

Synonym: Disodium NADH,NADH, disodium salt hydrate

Target: Others, Endogenous Metabolite

Se-Methylselenocysteine

T7727

Synonym: Se MSC,SeMCys,MSeC,Se-MSC,SeMSC

Target: BCL, IAP, Caspase

Fidaxomicin

T6194

Synonym: Tiacumicin B,OPT-80,Clostomicin B1,PAR-101

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic

Succinic acid

T2719

Synonym: Asuccin,Amber acid,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid

Target: Endogenous Metabolite

Amentoflavone

T3417

Synonym: Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin

Target: Apoptosis, P450, Phospholipase, Reactive Oxygen Species, Opioid Receptor, COX, Antibacterial, RSV, Antifungal

Rhoifolin

T2755

Synonym: Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy

Cysteamine hydrochloride

T6460

Synonym: 2-Mercaptoethylamine Hydrochloride,β-Mercaptoethylamine Hydrochloride,Thioethanolamine Hydrochloride,2-Aminoethanethiol Hydrochloride,Cysteamine HCl,Bekaptan

Target: Apoptosis, Others, Reactive Oxygen Species, Endogenous Metabolite, Autophagy

Caffeic Acid

T2807

Synonym:

Target: Lipoxygenase, Endogenous Metabolite, TRP/TRPV Channel

Wogonin

T2933

Synonym: Vogonin

Target: Apoptosis, Wnt/beta-catenin, CDK, Autophagy

Tauro-Obeticholic acid

Synonym: 17α-Ethynylestradiol,Ethinyl Estradiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Hexahydrocurcumin

TQ0288

Synonym:

Target: Reactive Oxygen Species, ROS, COX

Faropenem sodium

T5041

Synonym:

Target: Antibacterial, Antibiotic

Jatrorrhizine chloride

T4912

Synonym: Yatrorhizine chloride,Neprotine chloride

Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE

Capsiate

TN2429

Synonym:

Target: Antioxidant, TRP/TRPV Channel

Indole-3-carbinol

T2947

Synonym: I3C,3-Indolemethanol,Indole-3-Methanol

Target: E1/E2/E3 Enzyme, NF-κB, Aryl Hydrocarbon Receptor, Endogenous Metabolite, p53

Valproic Acid

T7064

Synonym: Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid

Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy

Medroxyprogesterone Acetate

T1261

Synonym: Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,Farlutin,Medroxyprogesterone (acetate)

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, Androgen Receptor, Endogenous Metabolite

Penicillin V Potassium

T1126

Synonym: Penicillin V potassium salt,Phenoxymethylpenicillin potassium salt

Target: Antibacterial, Antibiotic

Corticosterone

T0948L

Synonym: 17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)

Target: Glucocorticoid Receptor, Endogenous Metabolite

DMAPT

T11060

Synonym: Dimethylamino Parthenolide

Target: NF-κB

MRE-269

T3S2007

Synonym: MRE 269,ACT-333679,MRE269

Target: Prostaglandin Receptor

Lanatoside C

T1670

Synonym: Cedilanid,Ceglunate,Isolanid

Target: ATPase, Virus Protease, Autophagy

Aurantiamide acetate

TJS2216

Synonym: Asperglaucide

Target: Cysteine Protease

3β-Ursodeoxycholic acid

T13506

Synonym: Isoursodeoxycholic acid

Target:

PCO371

T16442

Synonym: 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-

Target: Thyroid hormone receptor(THR)

Berberine chloride

T0461

Synonym: Berberine hydrochloride,Benzodioxide,Natural Yellow 18

Target: Reactive Oxygen Species, Topoisomerase, Antibacterial, Antibiotic, Autophagy

3-Methyl-2-cyclopenten-1-one

T37152

Synonym:

Target: Endogenous Metabolite

Tramiprosate

T0883

Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed

Target: Beta Amyloid, GABA Receptor

Cefoxitin

T20643

Synonym: Rephoxitin,Cefoxitinum

Target: Cell wall, Antibacterial, Antibiotic

Yunaconitine

T5S1889

Synonym: Guayewuanine B

Target: Estrogen Receptor/ERR, Endogenous Metabolite

2-Methoxyestradiol

T2220

Synonym: NSC-659853,2-MeOE2,2-ME2

Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated, Endogenous Metabolite, HIF, Autophagy

(-)-(S)-Equol

T6491

Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

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カタログ番号	製品名
L9850	Orally Active Compound Library		2484 compounds
	A unique collection of 2484 of orally active compounds for high-throughput screening and high-content screening.

ライブラリー

Orally Active Compound Library

L9850

Compounds: 2484