Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50:3.8 nM)
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 27,000 | |||
5 mg | 在庫あり | ¥ 66,000 | |||
10 mg | 在庫あり | ¥ 104,500 | |||
25 mg | 在庫あり | ¥ 173,000 | |||
50 mg | 在庫あり | ¥ 243,500 | |||
100 mg | 在庫あり | ¥ 328,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 80,000 |
説明 | NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50:3.8 nM) |
ターゲット&IC50 | β-catenin/SCFβ-TrCP:3.8 nM (EC50) |
In vitro | NRX-252262 also induces S33E/S37A mutant β-catenin degradation at an even lower concentration of ~35?μM |
分子量 | 545.36 |
分子式 | C23H17Cl2F3N2O4S |
CAS No. | 2438637-61-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8 mg/mL (14.67 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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NRX-252262 2438637-61-5 Cytoskeletal Signaling Others Stem Cells Wnt/beta-catenin NRX252262 Beta catenin β-catenin Inhibitor NRX 252262 inhibit inhibitor