Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PRI-724 (C-82 prodrug) is a selective small-molecule inhibitor of β-catenin/CBP interaction.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 27,000 | |||
5 mg | 在庫あり | ¥ 57,000 | |||
10 mg | 在庫あり | ¥ 91,500 | |||
25 mg | 在庫あり | ¥ 152,500 | |||
50 mg | 在庫あり | ¥ 217,000 | |||
100 mg | 在庫あり | ¥ 294,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 68,500 |
説明 | PRI-724 (C-82 prodrug) is a selective small-molecule inhibitor of β-catenin/CBP interaction. |
In vivo | PRI-724 reduces liver fibrosis, and hepatic hydroxyproline levels, in HCV mice while attenuating αSMA induction. PRI-724 increased the levels of matrix metalloproteinase (MMP)-8 mRNA in the liver, along with elevated levels of intrahepatic neutrophils and macrophages/monocytes. In conclusion, PRI-724 ameliorates HCV-induced liver fibrosis in mice. PRI-724 is a drug candidate which possesses antifibrotic effect[1]. |
別名 | C-82 prodrug, Foscenvivint |
分子量 | 658.64 |
分子式 | C33H35N6O7P |
CAS No. | 1422253-38-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (83.51 mM)
Ethanol: 1.8 mg/mL (2.7 mM)
You can also refer to dose conversion for different animals. 詳細
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PRI-724 1422253-38-0 Cytoskeletal Signaling Stem Cells Wnt/beta-catenin C-82 prodrug PRI724 Foscenvivint PRI 724 Inhibitor inhibitor inhibit