Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. 3. Flavokawain A (Flavokavain A) may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-κB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
50 mg | 在庫あり | ¥ 10,000 | |||
100 mg | 在庫あり | ¥ 15,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,500 |
説明 | NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significantly reduce the expression of CDK1-inhibitory kinases, Myt1 and Wee1, and cause cyclin B1 protein accumulation leading to CDK1 activation in T24 cells. 3. Flavokawain A (Flavokavain A) may exert anti-inflammatory responses by suppressing LPS-induced expression of pro-inflammatory mediators via blockage of NF-κB-AP-1-JNK/p38 MAPK signaling pathways in the murine macrophages. |
植物由来 |
別名 | Flavokavain A |
分子量 | 314.33 |
分子式 | C18H18O5 |
CAS No. | 3420-72-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 29 mg/mL(92.3 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
You can also refer to dose conversion for different animals. 詳細
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Flavokawain A 3420-72-2 Apoptosis MAPK p38 MAPK EJ cells T24 anticarcinogenic inhibit Inhibitor chalcone Apoptotic bladder cancer Flavokavain A tumor inhibitor