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Search Results for " Apoptotic "

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天然化合物

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カタログ番号	製品名	別名	ターゲット
T63188	Apoptotic agent-2
	Apoptotic agent-2 is capable of downregulating Bcl-2 and upregulating Bax and caspase-3 to induce apoptosis, exhibiting anti-proliferative effects that can be used in cancer research.
T60851	Apoptotic agent-1
	Apoptotic agent-1 (Compound 8a) induces Fas receptor and Cyto C genes over-expression that is an apoptotic agent with high antiproliferative activity against cancer cells as well as low cytotoxic effect [1].
T63530	Apoptotic agent-3
	Apoptotic agent-3 utilizes a potential mitochondrial-mediated Bcl-2/Bax pathway and activates the caspase-3 pathway to promote apoptosis, exhibiting anti-proliferative effects that can be used to study cancer.
T76371	Tumor targeted pro-apoptotic peptide
	The compound, tumor-targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2), functions as an anti-tumor agent by disrupting mitochondrial membranes to induce apoptosis, demonstrating anticancer efficacy in mice [1].
T9118	KEA1-97		Apoptosis , Others , Caspase
	Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M). Kea1-97 destroys the interaction between thioredoxin and caspase 3 and activates caspases without affecting the activity ...		Apoptosis , Others , Caspase
T23861	CAY10526	CAY-10526,BTH,CAY 10526	Prostaglandin Receptor
	CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.		Prostaglandin Receptor
T7683	Adenosine amine congener	ADAC	Adenosine Receptor
	Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,.		Adenosine Receptor
T21919	UCF 101		Apoptosis
	UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.		Apoptosis
T8235	L-732138		Neurokinin receptor
	L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)		Neurokinin receptor
T2667	PIK-75		Apoptosis , DNA-PK , PI3K
	PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).		Apoptosis , DNA-PK , PI3K
TQ0138	K145 hydrochloride		Apoptosis , S1P Receptor
			Apoptosis , S1P Receptor
T12870	SCH79797 dihydrochloride		Apoptosis , Others , Protease-activated Receptor
	SCH79797 dihydrochloride is a selective antagonist of nonpeptide protease activated receptor 1 (PAR1).		Apoptosis , Others , Protease-activated Receptor
T22051	BU 224 hydrochloride		Imidazoline Receptor
	BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.		Imidazoline Receptor
T11571	HLY78	4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine	Wnt/beta-catenin
	HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt/β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling.		Wnt/beta-catenin
T9083	TC11	CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11	BCL , Caspase , CDK
	TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9.		BCL , Caspase , CDK
T2287	PIK-75 hydrochloride	PIK-75 HCl,PIK-75	Apoptosis , DNA-PK , PI3K
	PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.		Apoptosis , DNA-PK , PI3K
TP2306	Adipotide/FTPP(FatTargetedProapoptoticPeptide) Acetate		Others
	Adipotide as a prototype in a new class of candidate drugs that may be useful for treating obesity in humans		Others
T81283	RGD-targeted Proapoptotic Peptide
	RGD-Targeted Proapoptotic Peptide is a peptide that preferentially binds to integrins at sites of tumor angiogenesis through its C-terminal RGD-4C sequence (ACDCRGDCFC).
T24784	SF5	SF-5,SF 5	Apoptosis
	SF5 is an inhibitor of the apoptosis pathway. Which is through the JNK-p53-caspase apoptotic cascade.		Apoptosis
T77662	DJ4		Apoptosis
	DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range.		Apoptosis
T66703	Fmoc-D-Cha-OH		Apoptosis
	Fmoc-D-Cha-OH (FDCO) is an apoptotic DNase γ inhibitor that inhibits the release of HMGB1.		Apoptosis
T13689	Ethylene dimethanesulfonate		Apoptosis
	Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs. Ethylene dimethanesulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol.		Apoptosis
T67699L	ALK/ROS1 inhibitor 2e HCL	(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base)	Apoptosis
	ALK/ROS1 inhibitor 2e HCL possesses anti-apoptotic, anti-proliferative and anti-tumour activities.		Apoptosis
T4212	XMU-MP-1		Hippo pathway
	XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2.		Hippo pathway
T0459	Sulindac	Arthrocine,MK-231,Clinoril,Sulindac sulfoxide	COX , Autophagy
	Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl...		COX , Autophagy
T3953	Salermide		Apoptosis , Sirtuin
	Salermide is an inhibitor of Sirt1 and Sirt2, causing strong cancer-specific apoptotic cell death.		Apoptosis , Sirtuin
T13639	Deferasirox (Fe3+ chelate)		Apoptosis
	Deferasirox (Fe3+ chelate) is an orally available iron chelator with potential anticancer activity, inhibits the anti-apoptotic activity of MCL-1, and can be used to study iron overload.		Apoptosis
T77332	TV 3279		BCL , PKC
	TV 3279 is a novel ChE-MAI inhibitor , and the neuroprotective properties depend on their ability to induce the anti-apoptotic proteins PKC, Bcl-2, Bcl-x, and SOD, and to block the nuclear translocation of the pro-apopto...		BCL , PKC
T9014	SKI-178		Apoptosis , S1P Receptor
	SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ...		Apoptosis , S1P Receptor
TQ0076	KIRA6		IRE1
	KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 μM). It can trigger an apoptotic response.		IRE1
T16540	Piperazine Erastin		Ferroptosis
	Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.		Ferroptosis
T12644L	(S)-Thalidomide	(S)-(-)-Thalidomide	Apoptosis
	(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-isomer of Thalidomide with immunomodulatory, anti-inflammatory, anticancer, anti-angiogenic and pro-apoptotic activities, and is used in the study of leprosy erythema nodosu...		Apoptosis
T73577	TJ08		Apoptosis
	TJ08 is a 1,2,5-trisubstituted benzimidazole derivative with anticancer properties that effectively induces G1/S phase blockade while promoting apoptotic effects in a variety of cancer cells.		Apoptosis
T11209	EOAI3402143		DUB
	EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis. EOAI3402143 phenocopies the FAS induction and apoptotic sensitization of Usp5 knockdown and fully blocks melanoma tumor growth.		DUB
T77571	Bcl-B inhibitor 1		Apoptosis , BCL
	Bcl-B inhibitor 1 is a Bcl-B inhibitor with antitumor activity that binds to and inactivates pro-apoptotic proteins in the BH3 structural domain.		Apoptosis , BCL
T28206	NSC49652	NSC 49652,NSC-49652	Apoptosis
	NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.		Apoptosis
T9726	2’-OMe-Guanosine		Apoptosis , Nucleoside Antimetabolite/Analog
	2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.		Apoptosis , Nucleoside Antimetabolite/Analog
T70388	(S)-Enitociclib	VIP152	CDK
	(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that induces complete regression of MYC+ lymphomas by inhibiting RNA polymerase II-mediated transcription of anti-apoptotic and pro-survival proteins.		CDK
T6826	Emricasan	PF 03491390,IDN-6556	Influenza Virus , Caspase
	Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties. Emricasan has anti-inflammatory and anti-apoptotic activity and can be used in the treatment of infections and liver failure, etc. Emricasan a...		Influenza Virus , Caspase
T26585	AK301	AK-301,AK 301	Apoptosis , Microtubule Associated
	AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM). Colon cancer cells arrested in mitosis with AK301 readily underwent a ...		Apoptosis , Microtubule Associated
T9697	ASK1-IN-1		ASK
	ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays.		ASK
T10460	Batabulin	T138067	Apoptosis , Microtubule Associated
	Batabulin (T138067) is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to ce...		Apoptosis , Microtubule Associated
T0947	Dexamethasone acetate	Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471	Glucocorticoid Receptor , Mitophagy , IL Receptor , Annexin A , NOS , Antibacterial , Autophagy
	Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexa...
T31020	CP 461	OSI 461,UNII-68OJX9I7DT,CP-461,CP461	Apoptosis , PDE
	CP 461 (UNII-68OJX9I7DT), a specific PDE2A inhibitor, is a novel pro-apoptotic compound that inhibits cyclic GMP phosphodiesterase but not cyclooxygenase-1 or -2. CP 461 inhibits the growth of a variety of human tumor ce...		Apoptosis , PDE
T10706	CCI-006		Mitochondrial Metabolism
	CCI-006, a selective inhibitor and chemosensitizer for MLL-rearranged leukemia cells, disrupts mitochondrial respiration. This action leads to irreversible mitochondrial depolarization and triggers a pro-apoptotic unfold...		Mitochondrial Metabolism
T2129	Zaprinast		PDE
	Zaprinast is a cGMP-selective phosphodiesterase (PDE) inhibitor and a GPR35 agonist. It has a strong activating effect on rat GPR35 and a certain activating effect on human GPR35. It reduces vascular remodeling through a...		PDE
T10827	CK2/ERK8-IN-1	TMCB	Apoptosis , ERK , Casein Kinase , Pim , DYRK
	CK2/ERK8-IN-1 (TMCB) is a dual inhibitor of casein kinase 2 (CK2) (Ki: 0.25 µM) and ERK8 (IC50s: 0.50 μM) with pro-apoptotic efficacy. CK2/ERK8-IN-1 also binds to PIM1, DYRK1A, and HIPK2 (Kis: 8.65 µM, 11.9 µM, and 15.25...		Apoptosis , ERK , Casein Kinase , Pim , DYRK
T24855	TASIN-1 Hydrochloride	TASIN-1 HCl,TASIN 1 HCl,TASIN1 HCl	APC
	TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apopt...		APC
T15181	DuP-697		COX
	DuP-697 is an irreversible and specific inhibitor of COX-2 with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1. DuP-697 shows antiproliferative activity with an IC50 of 42.8 nM. DuP-697 exhibits antiangiogenic...		COX
T6778	BDA-366		BCL
	BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its antiapoptotic function, thereby transforming it into a pro-ap...		BCL

Compounds

Tumor targeted pro-apoptotic peptide

Target: Apoptosis, Others, Caspase

CAY10526

T23861

Synonym: CAY-10526,BTH,CAY 10526

Target: Prostaglandin Receptor

Adenosine amine congener

T7683

Synonym: ADAC

Target: Adenosine Receptor

Target: Neurokinin receptor

PIK-75

T2667

Synonym:

Target: Apoptosis, DNA-PK, PI3K

K145 hydrochloride

TQ0138

Synonym:

Target: Apoptosis, S1P Receptor

SCH79797 dihydrochloride

T12870

Synonym:

Target: Apoptosis, Others, Protease-activated Receptor

BU 224 hydrochloride

T22051

Synonym:

Target: Imidazoline Receptor

HLY78

T11571

Synonym: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine

Target: Wnt/beta-catenin

TC11

T9083

Synonym: CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11

Target: BCL, Caspase, CDK

PIK-75 hydrochloride

T2287

Synonym: PIK-75 HCl,PIK-75

Target: Apoptosis, DNA-PK, PI3K

Adipotide/FTPP(FatTargetedProapoptoticPeptide) Acetate

TP2306

Synonym:

Target: Others

RGD-targeted Proapoptotic Peptide

Ethylene dimethanesulfonate

T13689

Synonym:

Target: Apoptosis

ALK/ROS1 inhibitor 2e HCL

T67699L

Synonym: (R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base)

Target: Hippo pathway

Sulindac

T0459

Synonym: Arthrocine,MK-231,Clinoril,Sulindac sulfoxide

Target: COX, Autophagy

Salermide

T3953

Synonym:

Target: Apoptosis, Sirtuin

Deferasirox (Fe3+ chelate)

Target: Apoptosis, S1P Receptor

Synonym: (S)-(-)-Thalidomide

Target: Apoptosis, BCL

NSC49652

T28206

Synonym: NSC 49652,NSC-49652

Target: Apoptosis, Nucleoside Antimetabolite/Analog

Synonym: PF 03491390,IDN-6556

Target: Influenza Virus, Caspase

AK301

T26585

Synonym: AK-301,AK 301

Target: Apoptosis, Microtubule Associated

Target: Apoptosis, Microtubule Associated

Dexamethasone acetate

T0947

Synonym: Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy

CP 461

T31020

Synonym: OSI 461,UNII-68OJX9I7DT,CP-461,CP461

Target: Apoptosis, PDE

CCI-006

T10706

Synonym:

Target: Mitochondrial Metabolism

Target: Apoptosis, ERK, Casein Kinase, Pim, DYRK

TASIN-1 Hydrochloride

T24855

Synonym: TASIN-1 HCl,TASIN 1 HCl,TASIN1 HCl

カタログ番号	製品名	別名	ターゲット
TN1772	Isoastilbin		Anti-infection , Tyrosinase , Antibacterial
	Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, Isoastilbin has anti-acne an...		Anti-infection , Tyrosinase , Antibacterial
T3856	Tenuifoliside A		ERK , Others
	Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which is mediated by the inhibition of the NF-κB and MAPK pathways.		ERK , Others
TN2080	Pinoresinol	(+)-Pinoresinol	Apoptosis , NF-κB , CDK , p53
	Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st...		Apoptosis , NF-κB , CDK , p53
T3S0737	Flavokawain A	Flavokavain A	Apoptosis , p38 MAPK
	NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant...		Apoptosis , p38 MAPK
T5728	OsMundacetone	4-(3,4-Dihydroxyphenyl)-3-buten-2-one	Apoptosis , Reactive Oxygen Species
	OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.		Apoptosis , Reactive Oxygen Species
T8193	α-Thujone	Thujone,ALPHA-(-)-THUJONE	Apoptosis , Reactive Oxygen Species , GABA Receptor , AChR , Parasite , Autophagy
	α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
T13903	Stearoylethanolamide	N-(2-Hydroxyethyl)octadecanamide	Apoptosis
	Stearoylethanolamide(N-(2-Hydroxyethyl)octadecanamide) is a cannabinoid compound present in the brains of humans, rats, and mice with pro-apoptotic activity.		Apoptosis
T3395	Timosaponin AIII	Filiferin B,AneMarsaponin A3,Timosaponin A3	AChE , mTOR
	Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC...		AChE , mTOR
T5S0168	Atractylenolide II	2-Atractylenolide,Asterolide	Apoptosis , ERK , p38 MAPK , Akt , STAT
	1. Atractylenolide II (2-Atractylenolide) has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation , ERK and Akt inactivation, p53 dependent.		Apoptosis , ERK , p38 MAPK , Akt , STAT
T8092	Taurohyodeoxycholic acid sodium salt	Sodium taurohyodeoxycholate hydrate	Caspase
	Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.		Caspase
T2S1008	Oxysophoridine	Sophoridine N-oxide	Apoptosis , Antioxidant
	Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, ...		Apoptosis , Antioxidant
T4S0290	Araloside A	Chikusetsusaponin IV	RAAS , Fas/FasL
	Araloside A (Chikusetsusaponin IV) might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway.		RAAS , Fas/FasL
T8030	Ethyl pyruvate		Apoptosis , Antioxidant
	Ethyl pyruvate is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions.		Apoptosis , Antioxidant
T5311	Crocin (Gardenia Fruits Extract)		Others
	Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L.). Crocin has anti-inflammatory, anti-oxidative, anti-apoptotic, anti-asthma, anti-cancer, and hypolipidemic effects.		Others
T13864	Resolvin D1	RvD1	Apoptosis
	Resolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances macroph...		Apoptosis
T2S1396	3-O-Acetyloleanolic acid		Apoptosis
	3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells. Apoptosis was characterized by detection of cell surface annexin V and sub-G1 apoptotic cell populations.		Apoptosis
T3771	Methyl protodioscin	Smilax saponin B,NSC-698790	Apoptosis
	Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in h...		Apoptosis
TN3609	Catalposide	Hydroxybenzoyl catalpol	ERK , IL Receptor , TNF , NOS , NF-κB , NO Synthase , PPAR , Autophagy
	Catalposide is a potent inducer of (HO)-1 isolated from Catalpa ovate G. Don (Bignoniaceae). Catalposide possesses antioxidant, anti-apoptotic, anti-microbial, anti-tumoral, and anti-inflammatory properties.
TN6982	Diethyl phthalate	1,2-diethyl benzene-1,2-dicarboxylate	Apoptosis
	Diethyl phthalate (1,2-diethyl benzene-1,2-dicarboxylate) is a endocrine disrupter affecting the apoptotic system in PC12 cells. Diethyl phthalate is widely used in many plastics and personal care products.		Apoptosis
T3916	Ginsenoside F2		Apoptosis , Endogenous Metabolite , Autophagy
	Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitochondrial dysfunction.		Apoptosis , Endogenous Metabolite , Autophagy
T3759	3,4-Dimethoxycinnamic acid	Dimethylcaffeic acid,Caffeic acid dimethyl ether,O-Methylferulic acid	Apoptosis , Virus Protease , Reactive Oxygen Species
	3,4-Dimethoxycinnamic acid (O-Methylferulic acid) (O-Methylferulic acid) is a monomer found in Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated...		Apoptosis , Virus Protease , Reactive Oxygen Species
T3368	Alpha-Hederin	Helixin,Tauroside E,α-Hederin,Hederoside C	Apoptosis , Others
	Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.		Apoptosis , Others
T3S1775	Tectochrysin	NSC 80687,Techtochrysine,Techtochrysin	NF-κB , STAT
	1. Tectochrysin (Techtochrysine) has antioxidant effect. 2. Tectochrysin is promising inhibitors for the reversal of ABCG2-mediated drug transport. 3. Tectochrysin leads to apoptotic cell death in NSC-LC cells through ac...		NF-κB , STAT
T3914	Saikosaponin C		Beta Amyloid , Caspase
	Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.		Beta Amyloid , Caspase
TN2097	Pomolic acid		Apoptosis , Caspase , HIV Protease , AMPK
	Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediated intrinsic and death receptor-induced extrinsic pathways.		Apoptosis , Caspase , HIV Protease , AMPK
T2S0886	Terrestrosin D		Apoptosis , Others
	Terrestrosin D can induce apoptotic cell death and inhibit angiogenesis in xenograft tumor cells, cell cycle arrest and induction of apoptosis in cancer cells and endothelial cells might be plausible mechanisms of action...		Apoptosis , Others
T2S0500	Ilexsaponin A	Ilexsaponin A1	Others
	1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.		Others
T5715	(E)-Flavokawain A	FLAVOKAVAIN A(P)	Apoptosis , P450
	(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.		Apoptosis , P450
T8516	Levomenol	(-)-α-BISABOLOL	Others
	Levomenol ((-)-α-BISABOLOL) is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities.		Others
T3S1873	Talatisamine		Potassium Channel
	1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talat...		Potassium Channel
T3S0057	Dihydrochelerythrine	12,13-Dihydrochelerythrine	Antifungal
	1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application ...		Antifungal
T3030	L-Sophoridine	Sophoridine,Matridin-15-one	Others
	L-Sophoridine (Matridin-15-one) , a natural product obtained from medicinal plants, which has a variety of pharmacological effects, including anti-Y effects, and selectively induces apoptotic cell death in a variety of h...		Others
T2795	Amygdalin	Laetrile	Others
	Amygdalin (Laetrile) has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from intervertebral discs of rats induce...		Others
TN3049	4-Methoxycinnamyl alcohol		Others
	4-Methoxycinnamyl alcohol showed toxicity to MCF-7, HeLa and DU145 cancer cell lines with IC50 values of 14.24, 7.82 and 22.10 μg/mL, respectively. 4-Methoxycinnamyl alcohol was isolated from Foeniculum vulgare. 4-Methox...		Others
T7028	Licochalcone C	LICOCHALCONEC	Phosphatase , Antioxidant , Glucosidase
	Licochalcone C (LICOCHALCONEC) has potent antioxidant properties and inhibition of bacterial growth and cellular respiration. It has cardioprotection effect, via antioxidant, anti-inflammatory, and anti-apoptotic activit...		Phosphatase , Antioxidant , Glucosidase
T3051	Theaflavin-3-gallate	Theaflavine-3-Gallate	Others
	Theaflavin-3-gallate (Theaflavine-3-Gallate) can play a role in decreased intestinal cholesterol absorption via inhibition of micelle formation. Theaflavin-3-gallate has anticancer and apoptotic effects in non-small cell...		Others
T3862	Irigenin		NF-κB , Integrin
	Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha...		NF-κB , Integrin
T6S1653	Albiflorin	Alibiflorin	Reactive Oxygen Species
	1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced ...		Reactive Oxygen Species
T7032	Eupatorin		Others , P450
	Eupatorin has antiproliferative and antiangiogenic effects. Eupatorin has antiproliferative and cytostatic effects on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism. Eupatorin-induced cell death is ...		Others , P450
T6S0653	Linarin	Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine	TNF , AChE
	1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediat...		TNF , AChE
T36715	Tetrac	Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid	Apoptosis , EGFR
	Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking EGFR-mediated cell signaling in colorectal cancer cells.Tetrac...		Apoptosis , EGFR
T5679	(E)-Ferulic acid	trans-Ferulic acid,(E)-Coniferic acid	BCL , Ferroptosis , Wnt/beta-catenin , Endogenous Metabolite
	(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pr...
T7033	Rosmanol		Antioxidant , COX
	Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and a...		Antioxidant , COX
T3895	Polyphyllin I		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
	Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
T75319	Taurodeoxycholic acid	Taurodeoxychloic acid	Apoptosis , Calcium Channel , Caspase
	Taurodeoxycholic acid (Taurodeoxychloic acid) is a bile acid taurine conjugate of deoxycholic acid, a human metabolite that stabilizes mitochondrial membranes and reduces the formation of free radicals.Taurodeoxycholic a...		Apoptosis , Calcium Channel , Caspase
T4S1637	Gamma-Mangostin	Normangostin	Others , 5-HT Receptor
	1. gamma-Mangostin (Normangostin) as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells. 3. Gamma-Mangostin ...		Others , 5-HT Receptor
T0486L	Irinotecan Hydrochloride	Camptothecin 11 hydrochloride,CPT-11 hydrochloride	Topoisomerase , Autophagy
	Irinotecan Hydrochloride (CPT-11 hydrochloride) is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptoth...		Topoisomerase , Autophagy
T6S1369	Vitexin	Apigenin-8-C-glucoside	Antioxidant
	1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit...		Antioxidant
T3414	Morroniside		Apoptosis , MMP , Pyroptosis
	Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human umbilical vein endothelial cells, by inhib...		Apoptosis , MMP , Pyroptosis
T3779	Crocin II	Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B	Caspase , COX , NO Synthase
	Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres...		Caspase , COX , NO Synthase
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天然物製品

Isoastilbin

TN1772

Synonym:

Target: Anti-infection, Tyrosinase, Antibacterial

Synonym: (+)-Pinoresinol

Target: Apoptosis, NF-κB, CDK, p53

Flavokawain A

T3S0737

Synonym: Flavokavain A

Target: Apoptosis, p38 MAPK

OsMundacetone

T5728

Synonym: 4-(3,4-Dihydroxyphenyl)-3-buten-2-one

Target: Apoptosis, Reactive Oxygen Species

α-Thujone

T8193

Synonym: Thujone,ALPHA-(-)-THUJONE

Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, AChR, Parasite, Autophagy

Stearoylethanolamide

T13903

Synonym: N-(2-Hydroxyethyl)octadecanamide

Target: Apoptosis

Timosaponin AIII

T3395

Synonym: Filiferin B,AneMarsaponin A3,Timosaponin A3

Target: AChE, mTOR

Atractylenolide II

T5S0168

Synonym: 2-Atractylenolide,Asterolide

Target: Apoptosis, ERK, p38 MAPK, Akt, STAT

Taurohyodeoxycholic acid sodium salt

T8092

Synonym: Sodium taurohyodeoxycholate hydrate

Target: Caspase

Oxysophoridine

T2S1008

Synonym: Sophoridine N-oxide

Target: Apoptosis, Antioxidant

Araloside A

T4S0290

Synonym: Chikusetsusaponin IV

Target: RAAS, Fas/FasL

Ethyl pyruvate

T8030

Synonym:

Target: Apoptosis, Antioxidant

Crocin (Gardenia Fruits Extract)

3-O-Acetyloleanolic acid

Synonym: Smilax saponin B,NSC-698790

Target: Apoptosis

Catalposide

TN3609

Synonym: Hydroxybenzoyl catalpol

Target: ERK, IL Receptor, TNF, NOS, NF-κB, NO Synthase, PPAR, Autophagy

Diethyl phthalate

TN6982

Synonym: 1,2-diethyl benzene-1,2-dicarboxylate

Target: Apoptosis, Endogenous Metabolite, Autophagy

3,4-Dimethoxycinnamic acid

T3759

Synonym: Dimethylcaffeic acid,Caffeic acid dimethyl ether,O-Methylferulic acid

Target: Apoptosis, Virus Protease, Reactive Oxygen Species

Alpha-Hederin

T3368

Synonym: Helixin,Tauroside E,α-Hederin,Hederoside C

Target: Apoptosis, Others

Tectochrysin

T3S1775

Synonym: NSC 80687,Techtochrysine,Techtochrysin

Target: Beta Amyloid, Caspase

Pomolic acid

TN2097

Synonym:

Target: Apoptosis, Caspase, HIV Protease, AMPK

Terrestrosin D

T2S0886

Synonym:

Target: Apoptosis, Others

Ilexsaponin A

T2S0500

Synonym: Ilexsaponin A1

Target: Others

(E)-Flavokawain A

T5715

Synonym: FLAVOKAVAIN A(P)

Target: Apoptosis, P450

Levomenol

T8516

Synonym: (-)-α-BISABOLOL

Target: Potassium Channel

Dihydrochelerythrine

T3S0057

Synonym: 12,13-Dihydrochelerythrine

Target: Antifungal

L-Sophoridine

T3030

Synonym: Sophoridine,Matridin-15-one

4-Methoxycinnamyl alcohol

Synonym: LICOCHALCONEC

Target: Phosphatase, Antioxidant, Glucosidase

Theaflavin-3-gallate

T3051

Synonym: Theaflavine-3-Gallate

Target: NF-κB, Integrin

Albiflorin

T6S1653

Synonym: Alibiflorin

Target: Reactive Oxygen Species

Synonym: Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine

Target: TNF, AChE

Tetrac

T36715

Synonym: Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid

Target: Apoptosis, EGFR

(E)-Ferulic acid

T5679

Synonym: trans-Ferulic acid,(E)-Coniferic acid

Target: BCL, Ferroptosis, Wnt/beta-catenin, Endogenous Metabolite

Rosmanol

T7033

Synonym:

Target: Antioxidant, COX

Polyphyllin I

T3895

Synonym:

Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy

Taurodeoxycholic acid

T75319

Synonym: Taurodeoxychloic acid

Target: Apoptosis, Calcium Channel, Caspase

gamma-Mangostin

T4S1637

Synonym: Normangostin

Target: Others, 5-HT Receptor

Irinotecan Hydrochloride

T0486L

Synonym: Camptothecin 11 hydrochloride,CPT-11 hydrochloride

Target: Topoisomerase, Autophagy

Vitexin

T6S1369

Synonym: Apigenin-8-C-glucoside

Target: Apoptosis, MMP, Pyroptosis

Crocin II

T3779

Synonym: Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B

Target: Caspase, COX, NO Synthase

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01256	Caspase-10 Protein, Human, Recombinant (His)	Human	E. coli
	Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granz...
TMPH-01315	CASR Protein, Human, Recombinant (GST)	Human	E. coli
	CASR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 93.6 kDa and the accession number is P41180.
TMPH-01057	Caspase-8 Protein, Human, Recombinant (His)	Human	E. coli
	Caspase-8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.9 kDa and the accession number is Q14790.
TMPY-02700	BCL2 Protein, Human, Recombinant (His)	Human	E. coli
	BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPJ-00779	TNF alpha Protein, Rabbit, Recombinant	Rabbit	E. coli
	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor ty...
TMPY-02603	STAT6 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6...
TMPJ-00038	IL-7 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 a...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPH-03327	MBL2 Protein, Rat, Recombinant (His)	Rat	E. coli
	Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as...
TMPJ-01329	ATG5 Protein, Human, Recombinant	Human	E. coli
	ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic ce...
TMPH-00284	MBP-C Protein, Bovine, Recombinant (His)	Bovine	Baculovirus Insect Cells
	Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as...
TMPH-01548	IFI6 Protein, Human, Recombinant (B2M & His)	Human	E. coli
	Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis. However, it has also been shown to have a pro-apoptotic activity. Has an antiviral activity towar...
TMPH-01236	DFFB Protein, Human, Recombinant (His)	Human	E. coli
	Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
TMPK-00745	PGLYRP1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major he...
TMPK-00749	PGLYRP1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major he...
TMPY-01561	PIG3 Protein, Human, Recombinant (His)	Human	E. coli
	Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of ca...
TMPJ-00584	Bc1-w Protein, Human, Recombinant (His)	Human	E. coli
	Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing thre...
TMPY-03434	BMF Protein, Human, Recombinant (His)	Human	E. coli
	BMF(Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF...
TMPY-03974	Bim Protein, Human, Recombinant (His)	Human	E. coli
	BCL2L11, also known as Bim, belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. ...
TMPK-00077	EPO/Erythropoietin Protein, Human, Recombinant	Human	HEK293 Cells
	Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition im...
TMPJ-00661	PDCD5 Protein, Human, Recombinant (His)	Human	E. coli
	Programmed Cell Death Protein 5 (PDCD5) is a member of the PDCD5 family. PDCD5 is expressed in tumor cells during apoptosis, independent of apoptosis-inducing stimuli. This protein may function in the process of apoptosi...
TMPJ-01066	CYCS Protein, Human, Recombinant (His)	Human	E. coli
	Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as...
TMPH-01823	PERP Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway....
TMPH-01667	MT1X Protein, Human, Recombinant (GST)	Human	E. coli
	Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. May be involved in FAM168A anti-apoptotic...
TMPH-00535	Epstein-Barr virus (strain B95-8) BHRF1 Protein (His)	EBV	E. coli
	Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic pro...
TMPH-03267	CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)	Rat	E. coli
	Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which...
TMPH-02650	FCMR/FAIM3 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory...
TMPK-01139	TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (aa 21-295, His)	Human	HEK293 Cells
	Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic ce...
TMPY-02578	DKKL1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Dickkopf-like 1 (DKKL1) or soggy 1, is a glycoprotein unique to mammals that is expressed primarily in developing spermatocytes and localized in the acrosome of mature sperm. It is also expressed in the trophectoderm / p...
TMPH-03550	EsxA Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Virulence factor that is important for the establishment of infection in the host. EsxA is required for EsxB synthesis as well as secretion. Modulates host cell apoptotic pathways and mediates together with EsxB the rele...
TMPY-04936	BCL2A1 Protein, Human, Recombinant (His)	Human	E. coli
	B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in...
TMPK-00546	TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic ce...
TMPK-00723	RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPK-00351	RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)	Human	HEK293 Cells
	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPK-00768	ANXA1 Protein, Human, Recombinant (His)	Human	E. coli
	Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPK-00948	CDH17 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00952	CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-01224	CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated	Mouse	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPH-01898	PARL Protein, Human, Recombinant (Myc)	Human	E. coli
	Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apopt...
TMPY-00924	SMAC Protein, Human, Recombinant (His)	Human	E. coli
	Apoptosis is an essential processes required for normal development and homeostasis of all metazoan organisms. Second Mitochondria-Derived Activator of Caspases (Smac) or Direct IAP Binding Protein with low isoelectric p...
TMPK-00555	CDH17 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00473	CDH17 Protein, Rhesus macaque, Recombinant (His)	Rhesus	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00799	ANXA1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPK-01223	CDH17 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00953	CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00949	CDH17 Domain 7 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00947	CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00950	CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-01291	ANXA1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPJ-01059	CRADD Protein, Human, Recombinant	Human	E. coli
	Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD do...
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Caspase-10 Protein, Human, Recombinant (His)

TMPJ-01256

Species: Human

Expression System: E. coli

CASR Protein, Human, Recombinant (GST)

TMPH-01315

Species: Human

Expression System: E. coli

Caspase-8 Protein, Human, Recombinant (His)

TMPH-01057

Species: Human

Expression System: E. coli

BCL2 Protein, Human, Recombinant (His)

TMPY-02700

Species: Human

Expression System: E. coli

TNF alpha Protein, Rabbit, Recombinant

TMPJ-00779

Species: Rabbit

Expression System: E. coli

STAT6 Protein, Human, Recombinant (His)

TMPY-02603

Species: Human

Expression System: Baculovirus Insect Cells

IL-7 Protein, Mouse, Recombinant (His)

TMPJ-00038

Species: Mouse

Expression System: HEK293 Cells

MKK4 Protein, Mouse, Recombinant (His & GST)

TMPY-04572

Species: Mouse

Expression System: Baculovirus Insect Cells

MBL2 Protein, Rat, Recombinant (His)

TMPH-03327

Species: Rat

Expression System: E. coli

ATG5 Protein, Human, Recombinant

TMPJ-01329

Species: Human

Expression System: E. coli

MBP-C Protein, Bovine, Recombinant (His)

TMPH-00284

Species: Bovine

Expression System: Baculovirus Insect Cells

IFI6 Protein, Human, Recombinant (B2M & His)

TMPH-01548

Species: Human

Expression System: E. coli

DFFB Protein, Human, Recombinant (His)

TMPH-01236

Species: Human

Expression System: E. coli

PGLYRP1 Protein, Human, Recombinant (hFc)

TMPK-00745

Species: Human

Expression System: HEK293 Cells

PGLYRP1 Protein, Mouse, Recombinant (hFc)

TMPK-00749

Species: Mouse

Expression System: HEK293 Cells

PIG3 Protein, Human, Recombinant (His)

TMPY-01561

Species: Human

Expression System: E. coli

Bc1-w Protein, Human, Recombinant (His)

TMPJ-00584

Species: Human

Expression System: E. coli

BMF Protein, Human, Recombinant (His)

TMPY-03434

Species: Human

Expression System: E. coli

Bim Protein, Human, Recombinant (His)

TMPY-03974

Species: Human

Expression System: E. coli

EPO/Erythropoietin Protein, Human, Recombinant

TMPK-00077

Species: Human

Expression System: HEK293 Cells

PDCD5 Protein, Human, Recombinant (His)

TMPJ-00661

Species: Human

Expression System: E. coli

CYCS Protein, Human, Recombinant (His)

TMPJ-01066

Species: Human

Expression System: E. coli

PERP Protein, Human, Recombinant (His & Myc & SUMO)

TMPH-01823

Species: Human

Expression System: E. coli

MT1X Protein, Human, Recombinant (GST)

TMPH-01667

Species: Human

Expression System: E. coli

Epstein-Barr virus (strain B95-8) BHRF1 Protein (His)

TMPH-00535

Species: EBV

Expression System: E. coli

CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)

TMPH-03267

Species: Rat

Expression System: E. coli

FCMR/FAIM3 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02650

Species: Mouse

Expression System: E. coli

TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (aa 21-295, His)

TMPK-01139

Species: Human

Expression System: HEK293 Cells

DKKL1 Protein, Human, Recombinant (hFc)

TMPY-02578

Species: Human

Expression System: HEK293 Cells

EsxA Protein, S. aureus, Recombinant (His & SUMO)

TMPH-03550

Species: Staphylococcus aureus

Expression System: E. coli

BCL2A1 Protein, Human, Recombinant (His)

TMPY-04936

Species: Human

Expression System: E. coli

TIM-1/KIM-1/HAVCR1 Protein, Cynomolgus, Recombinant (His)

TMPK-00546

Species: Cynomolgus

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)

TMPK-00723

Species: Mouse

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)

TMPK-00351

Species: Human

Expression System: HEK293 Cells

ANXA1 Protein, Human, Recombinant (His)

TMPK-00768

Species: Human

Expression System: E. coli

CDH17 Protein, Human, Recombinant (hFc)

TMPK-00948

Species: Human

Expression System: HEK293 Cells

CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)

TMPK-00952

Species: Human

Expression System: HEK293 Cells

CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

TMPK-01224

Species: Mouse

Expression System: HEK293 Cells

PARL Protein, Human, Recombinant (Myc)

TMPH-01898

Species: Human

Expression System: E. coli

SMAC Protein, Human, Recombinant (His)

TMPY-00924

Species: Human

Expression System: E. coli

CDH17 Protein, Cynomolgus, Recombinant (His)

TMPK-00555

Species: Cynomolgus

Expression System: HEK293 Cells

CDH17 Protein, Rhesus macaque, Recombinant (His)

TMPK-00473

Species: Rhesus

Expression System: HEK293 Cells

ANXA1 Protein, Mouse, Recombinant (His)

TMPK-00799

Species: Mouse

Expression System: E. coli

CDH17 Protein, Mouse, Recombinant (His)

TMPK-01223

Species: Mouse

Expression System: HEK293 Cells

CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)

TMPK-00953

Species: Human

Expression System: HEK293 Cells

CDH17 Domain 7 Protein, Human, Recombinant (hFc)

TMPK-00949

Species: Human

Expression System: HEK293 Cells

CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00947

Species: Human

Expression System: HEK293 Cells

CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)

TMPK-00950

Species: Human

Expression System: HEK293 Cells

ANXA1 Protein, Cynomolgus, Recombinant (His)

TMPK-01291

Species: Cynomolgus

Expression System: E. coli

CRADD Protein, Human, Recombinant

TMPJ-01059

Species: Human

Expression System: E. coli

--------- More ---------

カタログ番号	製品名
L9000	Apoptosis Compound Library	1760 compounds
	A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;
L6140	Saccharide and Glycoside Natural Product Library	362 compounds
	A unique collection of 362 saccharides and glycosides compounds can be used for HTS and HCS；
L9420	Exosome Compound Library	76 compounds
	76 exosome-related compounds that can be used for high-throughput and high-content screening.
L9840	Anti-Alzheimer's Disease Compound Library	986 compounds
	A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.

ライブラリー

Apoptosis Compound Library

L9000

Compounds: 1760

Saccharide and Glycoside Natural Product Library

L6140

Compounds: 362

Exosome Compound Library

L9420

Compounds: 76

Anti-Alzheimer's Disease Compound Library

L9840

Compounds: 986