Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is used to manage HYPERTENSION and chronic HEART FAILURE in elderly patients.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 10,000 | |||
25 mg | 在庫あり | ¥ 14,500 | |||
50 mg | 在庫あり | ¥ 22,500 | |||
100 mg | 在庫あり | ¥ 38,000 | |||
200 mg | 在庫あり | ¥ 65,000 | |||
500 mg | 在庫あり | ¥ 112,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 9,000 |
説明 | Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is used to manage HYPERTENSION and chronic HEART FAILURE in elderly patients. |
ターゲット&IC50 | β1-adrenoceptor:0.8 nM |
細胞研究 | Cells are exposed to different concentrations of Nebivolol (10-7~10-5 M) for 1, 2, 4, 7 and 14 days. Cell proliferation is analyzed by bromodeoxyuridine (BrdU) incorporation, and cell apoptosis is detected by PI or annexin V staining.(Only for Reference) |
別名 | R 065824 hydrochloride, Nebivolol HCl, R-65824 |
分子量 | 441.9 |
分子式 | C22H25F2NO4·HCl |
CAS No. | 152520-56-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 4.4 mg/mL (10 mM)
DMSO: 44.2 mg/mL (100 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Nebivolol hydrochloride 152520-56-4 Apoptosis GPCR/G Protein Neuroscience Adrenergic Receptor R 065824 hydrochloride R-065824 Hydrochloride adrenergic blocking ischemic heart disease R65824 Nebivolol HCl R 065824 congestive heart failure coronary artery disease R065824 Nebivolol oral inhibit hypertension R 065824 Hydrochloride Inhibitor R065824 Hydrochloride Beta Receptor vasodilator R 65824 R-65824 R-065824 Nebivolol Hydrochloride inhibitor