Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 11,500 | |||
10 mg | 在庫あり | ¥ 16,500 | |||
25 mg | 在庫あり | ¥ 27,500 | |||
50 mg | 在庫あり | ¥ 47,000 | |||
100 mg | お問い合わせ | ¥ 71,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 16,000 |
説明 | (E/Z)-Necrosulfonamide is a novel inhibitor of MLKL. |
In vivo | Necrosulfonamide attenuates the spinal cord injury via necroptosis inhibition[1] |
動物実験 | Pathologic condition was detected using hematoxylin-eosin staining on injured spinal cord and other major organs. Necroptosis-related factors-RIP1, RIP3, and MLKL-were detected using Western blot. Detections on mitochondrial functions such as adenosine triphosphate generation and activities of superoxide dismutase and caspase-3 were also performed. Finally, ethologic performance was detected using a 21-point open-field locomotion test[1]. |
分子量 | 461.47 |
分子式 | C18H15N5O6S2 |
CAS No. | 432531-71-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (54.17 mM)
5% DMSO+95% Saline: 1.25 mg/mL (2.71 mM, suspension)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(E/Z)-Necrosulfonamide 432531-71-0 MAPK MLK Necrosulfonamide Inhibitor inhibitor inhibit