keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nepetin (6-Methoxyluteolin) has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 17,500 | |||
5 mg | 在庫あり | ¥ 52,500 | |||
10 mg | 在庫あり | ¥ 85,500 | |||
25 mg | 在庫あり | ¥ 141,500 | |||
50 mg | 在庫あり | ¥ 199,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 51,500 |
説明 | Nepetin (6-Methoxyluteolin) has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. |
In vitro | Using the human basophilic KU812F cells, we assessed the inhibitory effects of 6-Methoxyluteolin, isolated from Chrysanthemum zawadskii, in the FcαμRI-mediated allergic reaction. We determined that 6-Methoxyluteolin inhibited anti-FcαμRI α± chain antibody (CRA-1)-induced histamine release, as well as elevation of intracellular calcium concentration [Ca2+]i in a dose-dependent manner. Moreover, the inhibitory effects of 6-Methoxyluteolin on the cell surface expression and the mRNA level of the FcαμRI α± chain were determined by flow cytometric analysis and reverse transcription-polymerase chain reaction (RTPCR), respectively. |
植物由来 |
別名 | 6-Methoxyluteolin |
分子量 | 316.26 |
分子式 | C16H12O7 |
CAS No. | 520-11-6 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (31.62 mM)
You can also refer to dose conversion for different animals. 詳細
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Nepetin 520-11-6 GPCR/G Protein Immunology/Inflammation Membrane transporter/Ion channel Metabolism Neuroscience Calcium Channel Histamine Receptor Inhibitor 6-Methoxyluteolin inhibit inhibitor