Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin induces significant induction of cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells via down-regulation of EGFR/PI3K/STAT3 signaling and modulation of Bcl-2 family proteins. Nitroaspirin has antithrombotic and antiplatelet properties and acts as a direct and irreversible inhibitor of COX-1.
説明 | Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin induces significant induction of cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells via down-regulation of EGFR/PI3K/STAT3 signaling and modulation of Bcl-2 family proteins. Nitroaspirin has antithrombotic and antiplatelet properties and acts as a direct and irreversible inhibitor of COX-1. |
別名 | NCX 4016 |
分子量 | 331.28 |
分子式 | C16H13NO7 |
CAS No. | 175033-36-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (166.02 mM)
You can also refer to dose conversion for different animals. 詳細
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Nitroaspirin 175033-36-0 Apoptosis Immunology/Inflammation Neuroscience COX Inhibitor Cyclooxygenase NCX 4016 NCX4016 inhibit NCX-4016 inhibitor