Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by preventing cyclooxygenase from producing prostaglandins which can cause inflammation.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
50 mg | 在庫あり | ¥ 9,000 | |||
100 mg | 在庫あり | ¥ 12,000 | |||
200 mg | お問い合わせ | ¥ 18,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,000 |
説明 | Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by preventing cyclooxygenase from producing prostaglandins which can cause inflammation. |
ターゲット&IC50 | ATP systhesis:0.88 μM(Ki) |
In vivo | Fenbufen and its metabolites could be involved in mitochondrial toxicity through inhibition of ATP synthesis[1]. Fenbufen inhibited prostaglandin release by 80% and reduced rates of protein synthesis in normal muscle and in muscle undergoing hypertrophy in response to tenotomy of a synergist[3]. |
別名 | CL-82204, Lederfen |
分子量 | 254.28 |
分子式 | C16H14O3 |
CAS No. | 36330-85-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 47 mg/mL (184.8 mM)
DMSO: 47 mg/mL (184.8 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Fenbufen 36330-85-5 Apoptosis Immunology/Inflammation Membrane transporter/Ion channel Neuroscience Proteases/Proteasome ATPase COX Caspase anti-inflammatory tendinitis analgetic Inhibitor inhibit CL 82204 antipyretic ankylosing spondylitis CL-82204 antirheumatic Lederfen osteoarthritis CL82204 Cyclooxygenase inhibitor