Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Plx-4032 (Vemurafenib) is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 11,500 | |||
50 mg | 在庫あり | ¥ 16,500 | |||
100 mg | 在庫あり | ¥ 23,000 | |||
200 mg | 在庫あり | ¥ 41,500 | |||
500 mg | 在庫あり | ¥ 70,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Plx-4032 (Vemurafenib) is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma. |
In vivo | PLX-4032 and its related analogs are highly potent inhibitors of B-Raf activity, with 3-fold selectivity for the V600E mutation over the wild-type kinase.?In preclinical models, PLX-4032 and its analogs inhibited the growth of BRAFV600E-positive melanoma cell lines both in vitro and in vivo[1]. |
別名 | Vemurafenib |
分子量 | 489.92 |
分子式 | C23H18ClF2N3O3S |
CAS No. | 1029872-54-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (61.23 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Plx-4032 1029872-54-5 MAPK Raf Vemurafenib Plx 4032 Plx4032 18504-65-1 Inhibitor inhibitor inhibit