store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
50 mg | 在庫あり | ¥ 7,500 | |||
100 mg | 在庫あり | ¥ 11,000 | |||
200 mg | 在庫あり | ¥ 16,000 | |||
500 mg | 在庫あり | ¥ 25,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 9,000 |
説明 | Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. Propantheline Bromide is the bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. An aspartic acid residue present in the N-terminal portion of the third transmembrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax the bronchial muscle and reduce tone and motility of intestinal smooth muscle. |
別名 | Neopepulsan, Pro-Banthine, Neometantyl |
分子量 | 448.4 |
分子式 | C23H30BrNO3 |
CAS No. | 50-34-0 |
store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (133.81 mM)
You can also refer to dose conversion for different animals. 詳細
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Propantheline bromide 50-34-0 Neuroscience AChR Urination Propantheline Neopepulsan IBS Inhibitor mAChR Propantheline Bromide Muscarinic acetylcholine receptor cramps bladder Pro-Banthine Neometantyl bowel dysfunction inhibit inhibitor