Powder: -20°C for 3 years | In solvent: -80°C for 1 year
QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.
説明 | QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells. |
ターゲット&IC50 | ARFGAP1:1.5 µM (EC50) |
別名 | QS 11 |
分子量 | 567.68 |
分子式 | C36H33N5O2 |
CAS No. | 944328-88-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 100 mM
DMSO: 55 mg/mL (96.88 mM)
You can also refer to dose conversion for different animals. 詳細
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QS11 944328-88-5 GPCR/G Protein GTPase synergistic Wnt regenerative agonist signaling factors Inhibitor inhibit ADP-ribosylation QS 11 QS-11 inhibitor