keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and the formation of advanced glycosylation end products (AGEs).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 25,000 | |||
5 mg | 在庫あり | ¥ 63,500 | |||
10 mg | 在庫あり | ¥ 108,000 | |||
25 mg | 在庫あり | ¥ 174,500 | |||
50 mg | 在庫あり | ¥ 226,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 90,500 |
説明 | Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) is an inhibitor of AR and AGE formation and can be extracted from A. iwayomogi.Quercetin 3-gentiobioside inhibits the biological activity of aldose reductase (AR) and the formation of advanced glycosylation end products (AGEs). |
ターゲット&IC50 | AGE:109.46±1.41, AR:10.6±0.38 |
In vitro |
We led to isolation of Quercetin-3-gentiobioside was first reported on the isolation from A. iwayomogi. A. iwayomogi extracts showed significant inhibitor on AR and AGEs formation activities[1] We also determined quercetin 3-O-gentiobioside have antioxidant activity in vitro.[2] |
In vivo | Treatment with quercetin 3-O-gentiobioside (HF diet-induced obese mice; 0.1% Iso and Que) reduced blood glucose and serum insulin levels and improved glucose tolerance in obese mice. Meanwhile, serum triglyceride levels and liver morphology in the mice were significantly ameliorated by EO and isoquercitrin treatment. Total cholesterol levels in quercetin 3-O-gentiobioside treated mice were also reduced.[2] |
別名 | Quercetin-3-gentiobioside |
分子量 | 626.52 |
分子式 | C27H30O17 |
CAS No. | 7431-83-6 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (143.6 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Quercetin 3-gentiobioside 7431-83-6 Endocrinology/Hormones Metabolism Reductase Quercetin-3-gentiobioside Inhibitor inhibitor inhibit