Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 8,500 | |||
10 mg | 在庫あり | ¥ 12,000 | |||
25 mg | 在庫あり | ¥ 18,500 | |||
50 mg | 在庫あり | ¥ 26,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker. |
In vitro | PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
別名 | 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid, (2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine |
分子量 | 331.28 |
分子式 | C15H13N3O6 |
CAS No. | 927670-97-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 42.5 mg/mL (128.29 mM)
You can also refer to dose conversion for different animals. 詳細
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Thalidomide-NH-CH2-COOH 927670-97-1 PROTAC Ligand for E3 Ligase inhibit Ligands for E3 Ligase E3 ligase-recruiting Moiety Inhibitor Thalidomide NH CH2 COOH ThalidomideNHCH2COOH cereblon Thalidomide-NH-CH-2-COOH CRBN 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid Thalidomide (2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine inhibitor