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カタログ番号 | 製品名 | 別名 | ターゲット |
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T0213 | Thalidomide | Thalomid,Sedoval | Apoptosis , TNF , Autophagy , Ligand for E3 Ligase , Molecular Glues |
Thalidomide (Thalomid) is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. | |||
T12644L | (S)-Thalidomide | (S)-(-)-Thalidomide | Apoptosis |
(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-isomer of Thalidomide with immunomodulatory, anti-inflammatory, anticancer, anti-angiogenic and pro-apoptotic activities, and is used in the study of leprosy erythema nodosu... | |||
T9389 | Thalidomide-PEG4-Propargyl | Thalidomide-O-PEG4-Propargyl | E3 Ligase Ligand-Linker Conjugate |
Thalidomide-PEG4-Propargyl (Thalidomide-O-PEG4-Propargyl) is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker which can be used in PROTAC technology[1]. | |||
T18831 | Thalidomide-propargyl | Others , Ligand for E3 Ligase | |
Thalidomide-propargyl, a Thalidomide-derived Cereblon ligand, facilitates the recruitment of Cereblon. It can be attached to the protein ligand via a linker, producing IMiD-containing PROTACs. | |||
T40012 | Thalidomide-CH2CONH-C2-COOH | Others | |
Thalidomide-CH2CONH-C2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and linker used in PROTAC technology. | |||
T40013 | Thalidomide-O-CH2CONH-CH2COOH | Others | |
Thalidomide-O-CH2CONH-CH2COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and linker used in PROTAC technology. | |||
T40011 | Thalidomide-CH2CONH-C3-COOH | Others | |
Thalidomide-CH2CONH-C3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and linker used in PROTAC technology. | |||
T40503 | Thalidomide-5-methyl | Ligand for E3 Ligase | |
Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein. | |||
T9402 | Thalidomide-O-C4-NH2 hydrochloride | E3 Ligase Ligand-Linker Conjugate | |
Thalidomide-linker 9 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. | |||
T18807 | Thalidomide-NH-C4-NH-Boc | E3 Ligase Ligand-Linker Conjugate , Ligand for E3 Ligase | |
Thalidomide-NH-C4-NH-Boc is a synthesized conjugate used in PROTAC technology, combining a Thalidomide-based cereblon ligand with a linker. | |||
T7755 | Thalidomide 4-fluoride | E3 ligase Ligand 4 | IRAK , Ligand for E3 Ligase |
Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) ... | |||
T7753 | Thalidomide-O-COOH | Cereblon ligand 3,E3 ligase Ligand 3,TCE35031 | Others , Ligand for E3 Ligase |
Thalidomide-O-COOH (Cereblon ligand 3) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTACs. | |||
T7763 | Thalidomide-4-OH | Cereblon ligand 2,E3 ligase Ligand 2 | Ligand for E3 Ligase |
Thalidomide-4-OH (E3 ligase Ligand 2) (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used to recruit of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) is a linker to form PROTACs | |||
T9381 | Thalidomide 5-fluoride | H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro- | Ligand for E3 Ligase |
Thalidomide 5-fluoride (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-) is a thalidomide-based Cereblon ligand that binds to the IRAK4 protein ligand via a linker to form PROTACIRAK4 degrader-1. | |||
T9291 | Thalidomide-5-OH | 2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione | Others , Ligand for E3 Ligase |
Thalidomide-5-OH (2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione) is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a link... | |||
T40003 | Thalidomide-NH-C6-NH2 hydrochloride | Others , E3 Ligase Ligand-Linker Conjugate | |
Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology. | |||
T40019 | Thalidomide-5-NH2-CH2-COOH | Others | |
Thalidomide-5-NH2-CH2-COOH (compound 114) is a selective inhibitor of the protomyosin receptor kinase. It is a ligand for E3 ligase and has potential for studying one or more diseases. | |||
T15189 | Thalidomide-O-amido-C4-N3 | E3 ligase Ligand-Linker Conjugates 18,Cereblon Ligand-Linker Conjugates 4 | Others , Ligand for E3 Ligase |
Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker. | |||
T18819 | Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride | Others , Ligand for E3 Ligase | |
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker. Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride can be used as an immunomodulator for the treatment of cancer. | |||
T40016 | Thalidomide-NH-CH2-COOH | 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid,(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine | Ligand for E3 Ligase |
Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker. | |||
T18816 | Thalidomide-O-amido-C6-NH2 hydrochloride | Others , E3 Ligase Ligand-Linker Conjugate | |
Thalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, integrating a Thalidomide-based cereblon ligand with a linker, suitable for PROTAC synthesis. | |||
T40030 | Thalidomide 4'-ether-alkylC2-amine hydrochloride | halidomide-linker 6 | E3 Ligase Ligand-Linker Conjugate |
Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate. | |||
T9401 | Thalidomide-NH-PEG1-NH2 hydrochloride | 4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl | E3 Ligase Ligand-Linker Conjugate |
Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cere... | |||
T18818 | Thalidomide-O-amido-PEG-C2-NH2 hydrochloride | Others , E3 Ligase Ligand-Linker Conjugate | |
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-PEG-C2-NH2 hydrochloride can be us... | |||
T9382 | Thalidomide-NH-C2-PEG3-OH | H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]- | E3 Ligase Ligand-Linker Conjugate |
Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligand-linker conjugate. | |||
T7760 | Thalidomide-O-amido-C3-NH2 TFA | Cereblon Ligand-Linker Conjugates 16 TFA,E3 Ligase Ligand-Linker Conjugates 52 TFA | E3 Ligase Ligand-Linker Conjugate , Ligand for E3 Ligase |
Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-C3-NH2 TFA incorporates the Thalidomide based cereblon ligand and a linker... | |||
T77912 | Tz-Thalidomide | Epigenetic Reader Domain | |
Tz-Thalidomide is a tetrazine-modified Thalidomide (E3 ligase ligand) with some affinity for BRD4. | |||
T40031 | Thalidomide-O-C6-NH2 hydrochloride | 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride | E3 Ligase Ligand-Linker Conjugate |
Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) is a synthesized E3 ligase ligand-linker conjugate. | |||
T39377 | Thalidomide-PEG2-NH2 | Thalidomide-PEG2-NH2 | |
Thalidomide-PEG2-NH2 is a chemically synthesized E3 ligase ligand-linker conjugate consisting of a ligand derived from Thalidomide-based cereblon and a linker commonly employed in PROTAC technology. | |||
T12644 | (R)-Thalidomide | (R)-(+)-Thalidomide | Others |
(R)-Thalidomide is the R-enantiomer of Thalidomide, has sedative properties. | |||
T17918 | Thalidomide-O-amido-PEG2-C2-NH2 TFA | E3 Ligase Ligand-Linker Conjugates 24 TFA,Cereblon Ligand-Linker Conjugates 10 TFA | Others , E3 Ligase Ligand-Linker Conjugate |
Thalidomide-O-amido-PEG2-C2-NH2 TFA (E3 Ligase Ligand-Linker Conjugates 24 TFA) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG2-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand a... | |||
T39379 | Thalidomide-PEG3-NH2 | Thalidomide-PEG3-NH2 | |
Thalidomide-PEG3-NH2 is a synthesized conjugate comprising an E3 ligase ligand-linker conjugate that integrates a cereblon ligand based on Thalidomide and a linker employed in PROTAC technology. | |||
T7759 | Thalidomide-O-amido-C4-NH2 TFA | E3 ligase Ligand-Linker Conjugates 19 TFA,Cereblon Ligand-Linker Conjugates 6 TFA | E3 Ligase Ligand-Linker Conjugate |
Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) is a synthesized E3 ligase ligand-linker conjugate. | |||
T39378 | Thalidomide-O-C10-NH2 | Thalidomide-O-C10-NH2 | |
Thalidomide-O-C10-NH2 is a synthetic E3 ligase ligand-linker conjugate combining a cereblon ligand derived from Thalidomide with a linker crucial for PROTAC technology. | |||
T39950 | Thalidomide-amido-PEG2-NH2 | Thalidomide-amido-PEG2-NH2 | |
Thalidomide-amido-PEG2-NH2 is a synthetic conjugate of an E3 ligase ligand-linker that combines the Thalidomide-based cereblon ligand with a linker commonly utilized in PROTAC technology. | |||
T39382 | Thalidomide-NH-C8-NH2 | Thalidomide-NH-C8-NH2 | |
Thalidomide-NH-C8-NH2 is a synthetic conjugate of an E3 ligase ligand-linker, which combines a cereblon ligand based on Thalidomide with a specific linker utilized in PROTAC technology. | |||
T39496 | Thalidomide-O-C5-acid | Thalidomide-O-C5-acid | |
Thalidomide-O-C5-acid is a chemically synthesized conjugate that acts as an E3 ligase ligand-linker and combines the cereblon ligand derived from Thalidomide with a linker commonly utilized in PROTAC technology. | |||
T39917 | Thalidomide-O-C2-acid | Thalidomide-O-C2-acid | |
Thalidomide-O-C2-acid is a compound designed by synthesizing an E3 ligase ligand-linker conjugate. It comprises a cereblon ligand derived from Thalidomide and a linker commonly used in PROTAC technology. | |||
T40036 | Thalidomide-NH-PEG4-COOH | Thalidomide-NH-PEG4-COOH | |
Thalidomide-NH-PEG4-COOH is a conjugate comprising an E3 ligase ligand-linker, utilized in the synthesis of dCBP-1. dCBP-1 itself functions as a powerful and selective heterobifunctional degrader targeting p300/CBP. | |||
T39964 | Thalidomide-PEG4-NH2 hydrochloride | Thalidomide-PEG4-NH2 hydrochloride | |
Thalidomide-PEG4-NH2 hydrochloride is a compound synthesized as an E3 ligase ligand-linker conjugate. It encompasses the cereblon ligand derived from Thalidomide and a linker utilized specifically in PROTAC technology. | |||
T39644 | Thalidomide-O-C6-COOH | Thalidomide-O-C6-COOH | |
Thalidomide-O-C6-COOH is a synthetic conjugate comprising an E3 ligase ligand-linker, which combines the Thalidomide derived cereblon ligand with a PROTAC technology linker. | |||
T39643 | Thalidomide-O-C4-COOH | Thalidomide-O-C4-COOH | |
Thalidomide-O-C4-COOH is a synthetic conjugate compound, serving as an E3 ligase ligand-linker, which combines a cereblon ligand derived from Thalidomide and a linker utilized in PROTAC technology. | |||
T39895 | Thalidomide-Piperazine-PEG3-NH2 | Thalidomide-Piperazine-PEG3-NH2 | |
Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that combines the Thalidomide-based cereblon ligand with a linker commonly used in PROTAC technology, serving as an E3 ligase recruiter. | |||
T39511 | Thalidomide-O-C7-NH2 | Thalidomide-O-C7-NH2 | |
Thalidomide-O-C7-NH2 is a synthesized conjugate compound comprising an E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Thalidomide and a linker that is commonly employed in PROTAC... | |||
T39645 | Thalidomide-O-C7-acid | Thalidomide-O-C7-acid | |
Thalidomide-O-C7-acid is a compound created through the synthesis of an E3 ligase ligand-linker conjugate. It consists of a cereblon ligand derived from Thalidomide, combined with a linker that is commonly employed in PR... | |||
T40149 | Thalidomide-NH-PEG8-Ts | Thalidomide-NH-PEG8-Ts | |
Thalidomide-NH-PEG8-Ts is a chemically synthesized conjugate consisting of a Thalidomide-based cereblon ligand and an 8-unit PEG linker. This conjugate serves as an E3 ligase ligand-linker in PROTAC technology applicatio... | |||
T17919 | Thalidomide-O-amido-C6-NH2 TFA | E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate,Cereblon Ligand-Linker Conjugates 11 TFA,E3 Ligase Ligand-Linker Conjugates 25 TFA | Others , Ligand for E3 Ligase |
Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker. | |||
T7758 | Thalidomide-O-amido-PEG3-C2-NH2 TFA | E3 ligase Ligand-Linker Conjugates 14 TFA,Cereblon Ligand-Linker Conjugates 3 (TFA) | Others , E3 Ligase Ligand-Linker Conjugate , Ligand for E3 Ligase |
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG3-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand a... | |||
T39893 | Thalidomide-Piperazine-PEG2-NH2 | Thalidomide-Piperazine-PEG2-NH2 | |
Thalidomide-Piperazine-PEG2-NH2 is a synthetic E3 ligase ligand-linker conjugate that combines the cereblon ligand derived from Thalidomide with a linker commonly utilized in PROTAC technology. | |||
T39925 | Thalidomide-NH-PEG3-COOH | Thalidomide-NH-PEG3-COOH | |
Thalidomide-NH-PEG3-COOH is a conjugate of the E3 ligase ligand-linker synthesized compound, which integrates a cereblon ligand based on Thalidomide and a linker employed in PROTAC technology. |
カタログ番号 | 製品名 | 別名 | ターゲット |
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TN3098 | 5-hydroxythalidomide | 5,8,9,14-Tetraacetoxy-3-benzoyloxy-10,15-dihydroxypepluane | Others |
5-hydroxythalidomide is a natural product for research related to life sciences. The catalog number is TN3098 and the CAS number is 219916-77-5. |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-00541 | LON PROTEASE Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and natura... |