Powder: -20°C for 3 years | In solvent: -80°C for 1 year
UMB298 is a potent and selective CBP/P300 bromodomain inhibitor. UMB298 inhibits BRD4 with IC50 of 5193nM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 27,000 | |||
5 mg | 在庫あり | ¥ 67,000 | |||
10 mg | 在庫あり | ¥ 111,000 | |||
25 mg | 在庫あり | ¥ 181,000 | |||
50 mg | 在庫あり | ¥ 248,000 | |||
100 mg | 在庫あり | ¥ 340,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 68,500 |
説明 | UMB298 is a potent and selective CBP/P300 bromodomain inhibitor. UMB298 inhibits BRD4 with IC50 of 5193nM. |
ターゲット&IC50 | BRD4:5193nM |
In vitro | UMB298 inhibits MOLM13 and MM cells growth. UMB298 reduces the H3K27ac level similar to CBP30 and causes MYC depletion as a signature of CBP inhibition in acute myeloid leukemia. UMB298 down-regulates MYC expression in MOLM13 cells. |
分子量 | 479.01 |
分子式 | C27H31ClN4O2 |
CAS No. | 2266569-73-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL(41.75 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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UMB298 2266569-73-5 Chromatin/Epigenetic Epigenetic Reader Domain inhibit MOLM13 Inhibitor bromodomain UMB-298 selective potent UMB 298 CBP30 inhibitor