Powder: -20°C for 3 years | In solvent: -80°C for 1 year
UNC926 (UNC-926) inhibits L3MBTL1 (IC50: 3.9 μM). UNC926 also exhibits a low micromolar affinity for L3MBTL3. UNC926 inhibits binding of the 3xMBT domain to H4K20me1. It selectively and dose-dependently inhibits the L3MBTL13xMBT-H4K20me1 interaction. UNC926 has not an effect on the binding of 53BP1 to H4K20me1.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
2 mg | 在庫あり | ¥ 7,500 | |||
5 mg | 在庫あり | ¥ 10,500 | |||
10 mg | 在庫あり | ¥ 18,500 | |||
25 mg | 在庫あり | ¥ 35,500 | |||
50 mg | 在庫あり | ¥ 64,000 | |||
100 mg | 在庫あり | ¥ 103,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 12,000 |
説明 | UNC926 (UNC-926) inhibits L3MBTL1 (IC50: 3.9 μM). UNC926 also exhibits a low micromolar affinity for L3MBTL3. UNC926 inhibits binding of the 3xMBT domain to H4K20me1. It selectively and dose-dependently inhibits the L3MBTL13xMBT-H4K20me1 interaction. UNC926 has not an effect on the binding of 53BP1 to H4K20me1. |
ターゲット&IC50 | L3MBTL1:3.9 μM(Kd) |
別名 | UNC-926, UNC 926 hydrochloride |
分子量 | 337.25 |
分子式 | C16H21BrN2O |
CAS No. | 1184136-10-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 37.4 mg/mL(100 mM)
You can also refer to dose conversion for different animals. 詳細
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UNC926 1184136-10-4 Chromatin/Epigenetic Epigenetic Reader Domain 3xMBT L3MBTL1 methyl-lysine UNC 926 Hydrochloride H4K20me1 Inhibitor UNC-926 Hydrochloride L3MBTL3 inhibit UNC-926 UNC926 Hydrochloride UNC 926 UNC 926 hydrochloride inhibitor