Powder: -20°C for 3 years | In solvent: -80°C for 1 year
beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 28,000 | |||
5 mg | 在庫あり | ¥ 85,500 | |||
10 mg | 在庫あり | ¥ 137,000 | |||
25 mg | 在庫あり | ¥ 214,500 | |||
50 mg | 在庫あり | ¥ 289,500 | |||
100 mg | 在庫あり | ¥ 388,000 | |||
500 mg | 在庫あり | ¥ 776,000 |
説明 | beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity. |
In vitro | beta-Amyrone inhibits α-glucosidase AChE and fungal activity with IC50 values of 25 μM, 23 μM and 8 μg/mL, respectively[1]. In LPS-stimulated J774 cells, beta-Amyrone (2.5, 5, 10 μg/mL) inhibits NO production with an IC50 value of 4.61 μg/mL without obvious effects on cell viability[4]. beta-Amyrone (10 μg/mL) inhibits IL-6, IL-10 levels, and COX-2 expression at the dose of 10 μg/mL[4]. |
In vivo | In ear phenol-induced edema in Balb C mice, beta-Amyrone (0.1, 0.3, 0.6 mg/kg) inhibits ear edema formation in a dose-related manner[4]. |
植物由来 |
別名 | β-Amyron |
分子量 | 424.7 |
分子式 | C30H48O |
CAS No. | 638-97-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Insoluble
You can also refer to dose conversion for different animals. 詳細
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beta-Amyrone 638-97-1 DNA Damage/DNA Repair Immunology/Inflammation Metabolism Microbiology/Virology Neuroscience COX Antifection AChR PPAR antifungal AChE COX-2 PI3K-Akt Anti-inflammatory Fungal inflammation β-Amyron beta-Amyron β-Amyrone CHIKV Cyclooxygenase b-Amyron inhibit Inhibitor infection obesity Peroxisome proliferator-activated receptors b-Amyrone inhibitor