Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole A inhibits Hedgehog signaling with an IC50 of 1.9 μM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 7,500 | |||
5 mg | 在庫あり | ¥ 16,500 | |||
10 mg | 在庫あり | ¥ 28,000 | |||
25 mg | 在庫あり | ¥ 59,500 | |||
50 mg | 在庫あり | ¥ 102,000 | |||
100 mg | 在庫あり | ¥ 150,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 18,000 |
説明 | Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole A inhibits Hedgehog signaling with an IC50 of 1.9 μM. |
In vitro | Dynapyrazole A displays reversible inhibition of retrograde and anterograde intraflagellar transport in Chlamydomonas. In MA-104 cells infected with the RVA-NMTL virus, Dynapyrazole A (1-3 μg/mL) dose-dependently reduces viral titers with an EC50 of 0.73 μg/mL[1]. |
分子量 | 486.69 |
分子式 | C20H12ClIN4O |
CAS No. | 2226517-75-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (46.2 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
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Dynapyrazole A 2226517-75-3 Cytoskeletal Signaling Dynamin Inhibitor inhibitor inhibit