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T21798L |
Dynamin inhibitory peptide Acetate
|
Dynamin inhibitory peptide Acetate(251634-21-6 Free base) |
GTPase
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Dynamin inhibitory peptide Acetate is a peptide with the sequence Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro that inhibit the GTPase dynamin. |
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T64369 |
Dynamin IN-2
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Dynamin
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Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM). |
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TP1907L1 |
Dynamin inhibitory peptide, myristoylated acetate
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Dynamin inhibitory peptide, myristoylated acetate(251634-22-7 free base) |
Dynamin
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Dynamin inhibitory peptide, myristoylated acetate is a DynaMin inhibitor to interfere with the binding of amphiphysin with dynamin. DynaMin inhibitory peptide, myristoylated TFA is a membrane-permeant form of the peptide... |
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T1848 |
Dynasore
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Dynamin Inhibitor I |
Dynamin
,
Virus Protease
,
Autophagy
,
HSV
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Dynasore (Dynamin Inhibitor I), a cell-permeable chemical, can reversibly and non-competitivity inhibit GTPase activity of dynamin 1/2 (IC50: 15 μM in a cell-free assay). It also inhibits the mitochondrial dynamin Drp1, ... |
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TP1907 |
DynaMin inhibitory peptide, myristoylated
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Cell-permeable version of dynamin inhibitory peptide, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization. |
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TP2039 |
Dynamin inhibitory peptide, myristoylated (control)
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Control peptide version of dynamin inhibitory peptide, myristoylated, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. In contrast to dynamin inhibit... |
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T72952 |
Dynamin IN-1
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Dynamin IN-1 is a potent dynamin inhibitor with an IC 50 value of 1.0 µM . |
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T75796 |
Dynamin inhibitory peptide TFA
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Dynamin Inhibitory Peptide TFA competitively inhibits the binding of dynamin to amphiphysin, effectively preventing endocytosis. Additionally, this compound impedes the dopamine D3's influence on GABA A receptors [1]. |
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T6822 |
Hydroxy-Dynasore
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Dyngo-4a |
Dynamin
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Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively. |
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T1907 |
Mdivi-1
|
Mitochondrial division inhibitor 1 |
Apoptosis
,
Mitophagy
,
Dynamin
,
Autophagy
|
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Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM). Mdivi-1 inhibits mitochondrial autophagy. |
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T22445 |
Trimethyloctadecylammonium bromide
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Dynamin
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Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ. |
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T30479 |
Bis-T-23
|
Bis T-23,Bis-T 23,AG1717 |
HIV Protease
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Bis-T-23 is a promoter of actin-dependent dynamin oligomerization, an HIV-I integrase inhibitor, and a Telstar derivative. Bis-T-23 promotes actin-dependent dynamin oligomerization. Bis-T-23 can be used in studies of HIV... |
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T22981 |
Tetradecyltrimethylammonium bromide
|
MitMAB,Cetrimide,tetradecyl trimethyl ammonium bromide |
Dynamin
|
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Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure. |
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TP1947L |
P110 TFA
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|
Others
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P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. |
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T35548 |
Dynapyrazole A
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|
Dynamin
|
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Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding. Dynapyrazole A inhibits Hedgehog signaling with an IC50 of 1.9 μM. |
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T77772 |
MiTMAB
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MiTMAB, a selective dynamin inhibitor, targets the interaction between dynamin and phospholipids. This inhibitor can inhibit dynamin GTPase activity with a Ki value of 940 nM. |
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T22754 |
Dynole 34-2
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Others
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Dynamin I inhibitor |
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T38407 |
RTIL 13
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RTIL 13 is a highly effective inhibitor of dynamin GTPase, exhibiting an IC50 value of 2.3 μM for dynamin I GTPase. Furthermore, it selectively interacts with the pleckstrin homology lipid binding domain. This compound e... |
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T37023 |
MB 0223
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Dynamin-related GTPase DRP1 partial inhibitor (IC50 = 1.2 μM). Selective for DRP1 over other dynamin-related GTPases, OPA1 and DYN1. Increases mitochondrial DNA levels in mfn1- knockout MEFs deficient in mitochondrial fu... |
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TP1947 |
P110
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Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen... |
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T83891 |
Sulfonadyn-47
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Sulfonadyn-47 is a dynamin inhibitor that effectively inhibits dynamin GTPase activity with an IC50 of 3.5 µM in cell-free assays. Additionally, it disrupts clathrin-mediated endocytosis in U2OS cells (IC50 = 27.3 µM) an... |
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T61488 |
Dynole 2-24
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Dynole 2 24 is an indole-based dynamin GTPase inhibitor ( IC 50 =0.56 μM for dynamin I). Dynole 2 24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC (CME) =1.9 μM). Dynole 2 2... |
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T72894 |
Clathrin-IN-2
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Clathrin-IN-2 is a potent inhibitor of clathrin-mediated endocytosis (CME), demonstrating an IC50 value of 2.3 μM. Additionally, it exhibits inhibitory effects on dynamin I GTPase, with an IC50 of 7.7 μM. |
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T68788 |
Ellipticine quinone
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Ellipticine quinone, also known as NSC-383230, is a Drp1 inhibitor. rpitor1 and Drpitor1a inhibited the GTPase activity of Drp1 without inhibiting the GTPase of dynamin 1. Ellipticine quinone showed greater potency tha... |
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T73456 |
DRP1i27
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DRP1i27, a potent human dynamin-related protein 1 (Drp1) inhibitor, targets the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. It mitigates Drp1-mediated mitochondrial fission in cell line models and ... |
