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T14766 |
BPH-715
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Others
,
Parasite
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BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth. With an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells[1]. |
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T10586L |
BPH-1358
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NSC50460 |
Others
,
Antibacterial
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BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. a... |
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T30563 |
BPH-252
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BPH 252 |
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BPH-252 is a bioactive chemical. |
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T30567 |
BPH-675
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BPH 675 |
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BPH-675 is a bioactive chemical. |
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T30569 |
BPH-742
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BPH 742,BPH742 |
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BPH-742 is a bioactive chemical. |
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T30564 |
BPH-608
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BPH-608 is a bioactive chemical. |
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T10587 |
BPH-652
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Others
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BPH-652 is an S. aureus dehydrosqualene synthase (CrtM) inhibitor (Ki: 1.5 nM; IC50: 100-300 nM for S. aureus pigment formation). |
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T23815 |
BPH-651
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BPH651,3ACW,3-ACW,3 ACW |
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BPH-651 is a CrtM inhibitor. |
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T30568 |
BPH-676
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BPH-676 is a bioactive chemical. |
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T23814 |
BPH-1218
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BPH1218 |
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BPH-1218 is a SQS inhibitor. |
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T30570 |
BPH-830
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BPH830 |
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BPH-830 is a bioactive chemical. |
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T30566 |
BPH-629
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BPH629 |
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BPH-629 is a bioactive chemical. |
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T30565 |
BPH-628
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BPH628 |
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BPH-628 is a bioactive chemical. |
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T72587 |
BPH-1358 mesylate
|
NSC50460 mesylate |
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BPH-1358 mesylate (NSC50460 mesylate), a highly effective inhibitor of both human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS), exhibits IC50 values of 1.8 μM and 110 nM, respectively... |
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T10586 |
BPH-1358 free base
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NSC50460 free base |
Others
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|
BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 μM) and is active against S. aureus in vitro (MIC ~250 ng... |
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T60300 |
BPH-1086
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BPH-1086 (compound 10) is an inhibitor of IspH. IspH domain fused with ribosomal protein S1 (RPS1) can bind to mRNA or form part of the bacterial ribosome [1] [2]. |
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T0488 |
Finasteride
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MK-906 |
Reductase
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Finasteride (MK-906) is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM. |
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T0091 |
Alfuzosin hydrochloride
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SL 77499-10,Alfuzosin HCl |
Adrenergic Receptor
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Alfuzosin hydrochloride (Alfuzosin HCl) is an α1 adrenergic receptor antagonist. It applies to treat benign prostatic hyperplasia (BPH). |
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T1504 |
Silodosin
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KAD 3213,KMD 3213 |
Adrenergic Receptor
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Silodosin (KAD 3213) is an alpha-Adrenergic Blocker. The mechanism of action of silodosin is as an Adrenergic alpha-Antagonist. |
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T21366 |
Sapropterin free base
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BPH4,Dapropterin,6R-BH4,Tetrahydro-6-biopterin,THB,Phenoptin |
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Sapropterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of dopamine, epinephrine, melatoni... |
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T6461 |
Dapoxetine hydrochloride
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LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy |
5-HT Receptor
,
Serotonin Transporter
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Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation. |
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T0039 |
Dapoxetine
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Dapoxetina,Dapoxetinum |
Others
,
5-HT Receptor
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Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. |
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T36712 |
BPHA
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MMP-2/MMP-9 Inhibitor II |
MMP
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BPHA (MMP-2/MMP-9 Inhibitor II) is a potent, selective and orally active inhibitor of MMP-2, MMP-9 and MMP-14 with IC50s of 12 nM, 16 nM and 17 nM, respectively.BPHA does not inhibit MMP-1, -3 and -7 (IC50s of 974, >1000... |
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T27798 |
Lapisteride
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CS891B,CS-891,CS-891B,CS891 |
Others
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Lapisteride (CS-891) a steroidal 5α-reductase inhibitor is used to treat benign prostatic hyperplasia (BPH) and androgenetic alopecia and may be effective in preventing or treating AGA . |
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T14843 |
Bifluranol
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BX341 |
Androgen Receptor
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Bifluranol (BX341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic hyperplasia (BPH). |
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T6701 |
Terazosin hydrochloride dihydrate
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Flotrin dihydrate,Terazosin HCl Dihydrate,Dysalfa dihydrate,Heitrin dihydrate |
Adrenergic Receptor
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Terazosin hydrochloride dihydrate (Heitrin dihydrate) is a selective α1-adrenoceptor antagonist, used for treatment of symptoms of an enlarged prostate (BPH). |
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T0197 |
Terazosin hydrochloride
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Terazosin HCl,Terazosine,Blavin,Hytrin,Zayasel,Fosfomic |
Adrenergic Receptor
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Terazosin hydrochloride (Hytrin) , a selective alpha1-antagonist, can treat the benign prostatic hyperplasia (BPH). It also can lower blood pressure, so it is a drug of choice for patients with prostate enlargement and h... |
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T0210L |
Tamsulosin
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LY253351 free base,HSDB7744,(R)-(-)-YM12617 free base,Harnal-D,Flowmax,HSDB 7744,HSDB-7744 |
Adrenergic Receptor
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|
Tamsulosin ((R)-(-)-YM12617 free base) is an alpha1A adrenergic receptor antagonist for the symptomatic treatment of benign prostatic hyperplasia (BPH). Tamsulosin is used to treat difficulty urinating, a common symptom ... |
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T69492 |
Ozarelix
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|
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Ozarelix is a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors. Mechanistically, LHRH antag... |
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T70396 |
Fexapotide triflutate
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Fexapotide triflutate is a caspase and TNF signaling pathway activator used to treat benign prostatic hyperplasia (BPH). |
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T71904 |
Chlormadinone (free base)
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Chlormadinone (free base) is a synthetic steroid hormone and antagonist at androgen and estrogen receptors used to treat BPH and polycystic ovary syndrome. It also promotes osteoblast differentiation and Ca deposition in... |
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T76275 |
Fexapotide
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Fexapotide (NX-1207 free acid) selectively induces apoptosis, effectively reducing prostate volume at the cellular level. This compound is applicable in the research of lower urinary tract symptoms (LUTS) and benign pros... |
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T61729 |
Terazosin
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Terazosin, a quinazoline derivative, is an orally active and competitive antagonist of α1-adrenoceptors. Its mechanism of action involves relaxing blood vessels and promoting bladder opening. Terazosin exhibits therapeut... |
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T21668 |
Finasteride acetate
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Finasteride (MK-906) acetate is a potent and competitive 5α-reductase inhibitor, with an IC 50 of 4.2 nM for type II 5α-reductase. The affinity of Finasteride acetate for type II 5α-reductase enzyme was approximately 100... |
