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T82762 |
Cdc25A (80-93) (human)
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Cdc25A (80-93) (human) is a polypeptide implicated in the regulation of cell proliferation and tumorigenesis through modulation of cyclin D1 expression and facilitation of the G1/S phase transition. This compound has app... |
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T4671 |
BN82002
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CDC25 Phosphatase Inhibitor I |
Phosphatase
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T4327 |
Prexasertib dihydrochloride
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LY2606368 (dihydrochloride),Prexasertib HCl,LY2606368 |
Apoptosis
,
Chk
,
S6 Kinase
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Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmol/L). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively. |
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T4310 |
Prexasertib
|
LY2606368 |
Apoptosis
,
Chk
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Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity. |
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T7078 |
NSC 95397
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Apoptosis
,
Phosphatase
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NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively). |
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T16357 |
DA-3003-1
|
NSC 663284 |
Phosphatase
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DA-3003-1 (DA-3003-1) is a membrane-permeable, potent and selective Cdc25 dual specificity phosphatase inhibitor with antitumor activity that inhibits Cdc25B2, Cdc25A, Cdc25B2 and Cdc25C. |
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T11929 |
M2N12
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Phosphatase
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M2N12 also has promising activity against Cdc25A and Cdc25B with IC50 values of 0.53 μM and 1.39 μM. Anti-tumor activity. M2N12 is a potent and highly selective cell division cycle 25C protein phosphatase (Cdc25C) inhi... |
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T12263L |
NSC305787 hydrochloride
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(Rac)-NSC305787 hydrochloride |
Others
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T20491 |
NSC-672121
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NSC-672121 is an inhibitor of Cdc25A. It is also a Vitamine K3 analog. |
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T38447 |
BN82002 hydrochloride
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BN82002 hydrochloride is a potent, selective, and irreversible inhibitor of the CDC25 phosphatase family. It inhibits CDC25A, CDC25B2, CDC25B3, CDC25C, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 μM, resp... |
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T73526 |
M5N36
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M5N36, a potent and selective inhibitor of Cdc25C, demonstrates IC50 values of 0.15 µM for Cdc25A, 0.19 µM for Cdc25B, and 0.06 µM for Cdc25C. It exhibits anti-proliferative activity and enhances the expression of p-CDK1... |
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T81377 |
PROTAC NSD3 degrader-1
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PROTACs
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PROTAC NSD3 degrader-1 (compound 56) is a targeted degradation agent for the Nuclear receptor binding SET domain protein NSD3. It effectively induces the degradation of NSD3 in NCI-H1703 and A549 lung cancer cell lines, ... |
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T68981 |
PD-321852
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PD-321852 is a small-molecule Chk1 inhibitor, which potentiates gemcitabine-induced clonogenic death in a panel of pancreatic cancer cell lines and evaluated the relationship between endpoints associated with Chk1 inhibi... |
