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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T0455 | Clozapine | HF 1854,LX 100-129 | Dopamine Receptor , Adrenergic Receptor , AChR |
Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a... | |||
T72112 | Clozapine N-oxide dihydrochloride | AChE | |
Clozapine N-oxide dihydrochloride is a derivative of Clozapine and an agonist of human muscarinic design receptors (DREADDs) that crosses the blood-brain barrier.Clozapine N-oxide dihydrochloride induces activation of DR... | |||
T4494 | CLOZAPINE N-OXIDE | Dopamine Receptor , 5-HT Receptor , AChR , Drug Metabolite | |
Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide is also a dopa... | |||
T84365 | Clozapine Analogues | ||
T69129 | Clozapine HCl | ||
Clozapine HCl is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serot... | |||
TMIH-0166 | Clozapine-d8 | ||
Clozapine-d8 is a deuterated compound of Clozapine. | |||
TMIH-0376 | N-Desmethyl clozapine-d8 Hydrochloride | ||
N-Desmethyl clozapine-d8 Hydrochloride is a deuterated compound of N-Desmethyl clozapine Hydrochloride. N-Desmethyl clozapine Hydrochloride has a CAS number of 1189888-77-4. | |||
TMIH-0375 | N-Desmethyl clozapine-d8 | ||
N-Desmethyl clozapine-d8 is a deuterated compound of N-Desmethyl clozapine. | |||
T9019 | JHU37152 | JHU 37152 | AChR |
JHU37152 (JHU 37152) is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. ... | |||
T9018 | JHU37160 | JHU 37160 | AChR |
JHU37160 (JHU 37160) is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. ... | |||
T11078 | Deschloroclozapine | Serotonin Transporter | |
Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. | |||
T5158 | N-Desmethylclozapine | Desmethylclozapine,Normethylclozapine,Norclozapine | Virus Protease , Dopamine Receptor , 5-HT Receptor , Opioid Receptor , AChR , Drug Metabolite |
N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist at δ-opioid receptors. | |||
T21629 | Loxapine | Dopamine Receptor , 5-HT Receptor | |
Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class ... | |||
T26763 | Belaperidone | LU111995,LU-111995,LU 111995 | |
Belaperidone is an antipsychotic drug. It has a clozapine-like receptor profile and affinities for dopamine D(4) and 5-hydroxytryptamine(2A) receptors. LU111995 prolongs the Q-T interval to a limited degree and is not ar... | |||
T68706 | Olanzapine HCl | ||
Olanzapine HCl is an atypical antipsychotic. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar disorder. Olanzapine is structurally similar to clozapine and quet... |