|
T124358 |
Deferoxamine
|
Deferoxamine B,Desferrioxamine B |
Apoptosis
,
Antioxidant
,
HIF
,
Autophagy
|
|
Deferoxamine（Desferrioxamine B） is an iron chelator (binds Fe(III) and many other metal cations) that inhibits neuronopathy, may be used to modify the reduction of iron accumulation and deposition in tissues, and may imp... |
|
T1637 |
Deferoxamine Mesylate
|
desferrioxamine B,Desferrioxamine B mesylate,DFO,DFOM |
Mitophagy
,
Beta Amyloid
,
Others
,
Ferroptosis
,
HIF/HIF Prolyl-Hydroxylase
,
Autophagy
|
|
Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and i... |
|
T35994 |
Erastin2
|
Erastin2 |
|
|
Erastin2 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.[1] [2] It inhibits glutamate release in CCF-STTG1 cells (IC50 = 0.0035 µM).[2] It induces cell death in HAP1 cells... |
|
T83871 |
Ferroptocide
|
|
|
|
Ferroptocide, a thioredoxin (Trx) inhibitor and pleuromutilin derivative, exhibits inhibitory activity against Trx in ES-2 ovarian cancer cells at a concentration of 20 µM and demonstrates cytotoxicity towards these cell... |
