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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T8956 | BC-1258 | BC-1258 | Apoptosis |
BC-1258 is a unique small molecule F-box/LRR-repeat protein 2 (FBXL2) activator. | |||
T5821 | BC-1215 | Others , Ligand for E3 Ligase | |
BC-1215 is an inhibitor of F-box protein 3 (FBXO3, a ubiquitin E3 ligase component, IC50=0.9 μg/mL for IL-1β release). | |||
T23371 | SMER3 | SMER 3 | Others , Ligand for E3 Ligase |
SMER3 is an inhibitor of the Skp1-Cullin-F-box (SCF)(Met30) ubiquitin ligase, a member of the SCF E3-ligase family, which regulates diverse cellular processes including transcription, cell-cycle control and immune respon... | |||
T4603 | PEO-IAA | 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid | Others |
PEO-IAA (2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid) is a novel potent auxin antagonist. | |||
T78194 | Skp2 inhibitor 2 | E1/E2/E3 Enzyme | |
Skp2 inhibitor 2 (14f) impedes the F-box protein S-phase kinase-associated protein 2 (Skp2), demonstrating an IC50 of 10.2 μM against Skp2-Cks1. This compound targets Skp2, a component of cullin-RING ligases that recruit... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-01326 | FBXO44 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. FBXO44 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag.... | |||
TMPH-02651 | Fbxo3 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and ... | |||
TMPK-00044 | SKP1 Protein, Human, Recombinant (His, Avi) | Human | HEK293 Cells |
The S-phase Kinase-Associated Protein 1 (SKP1) is a core component of the SKP1, Cullin 1, F-box protein (SCF) complex, an E3 ubiquitin ligase that serves to poly-ubiquitinate a vast array of protein targets as a signal f... | |||
TMPK-00045 | SKP1 Protein, Human, Recombinant (His, Avi), Biotinylated | Human | HEK293 Cells |
The S-phase Kinase-Associated Protein 1 (SKP1) is a core component of the SKP1, Cullin 1, F-box protein (SCF) complex, an E3 ubiquitin ligase that serves to poly-ubiquitinate a vast array of protein targets as a signal f... | |||
TMPJ-00331 | IFNAR1 Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells |
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-... | |||
TMPH-02131 | SKP2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle pr... | |||
TMPH-02633 | TRIM21 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of... | |||
TMPH-02632 | TRIM21 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of... |