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カタログ番号 | 製品名 | 別名 | ターゲット |
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TP1365L | Parasin I acetate(219552-69-9 free base) | Antibacterial | |
Parasin I acetate is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus). | |||
T6014 | FRAX597 | PAK | |
FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM). | |||
T2078 | Fimepinostat | CUDC-907,PI3K/HDAC Inhibitor,CUDC 907 | Apoptosis , PI3K , HDAC |
Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, C... | |||
T62095 | TRK-IN-19 | Others | |
TRK-IN-19 (Compound I-10 ) is a potent inhibitor of TRK with IC50 values of 1.1 nM for TRKA and 5.3 nM for TRKAG595R. TRK-IN-19 has shown potential research value in cancer disease. | |||
TP1365 | Parasin I | ||
Parasin I is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus). | |||
T126164 | De-O-methylprosolanapyrone I | Others | |
De-O-methylprosolanapyrone I is a useful organic compound for research related to life sciences. The catalog number is T126164 and the CAS number is 1239892-19-3. | |||
T82234 | HCAIX-IN-19 | Others | |
hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/hCAIX = 117). | |||
T40893 | Estrogen receptor modulator 6 | Others | |
Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for... | |||
TP1443 | Parasin I (TFA)(219552-69-9,free) | Parasin I (TFA) | |
Parasin I (TFA) is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity[1]. | |||
T61491 | (R)-ND-336 | Others | |
(R)-ND-336 is a highly potent and selective MMP-9 inhibitor, displaying a K i value of 19 nM. It also exhibits inhibitory activity against MMP-2 (K i = 127 nM) and MMP-14 (K i =119 nM). With its significant potential, (R... | |||
T79648 | CDK2-IN-19 | CDK | |
CDK2-IN-19 (Compound 32) is a selective, orally active inhibitor of CDK2 (K i: 0.18 nM) that exhibits anticancer activity in mice with OVCAR3 tumors [1]. | |||
T73372 | GNE-2256 | Others | |
GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM. | |||
T79325 | 5-HT6 agonist 1 | 5-HT Receptor | |
Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting platelet aggregation. It demonstrates high metabolic stability [1]. | |||
T79756 | Beclin1-ATG14L interaction inhibitor 1 | Autophagy | |
Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L. It impedes the formation of complex I in the lipid kinase VPS34, thus inhibiting aut... | |||
T79373 | A3AR agonist 2 | Adenosine Receptor | |
Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM. This compound is utilized in research pertaining to inflammato... | |||
T21949 | Calpain Inhibitor XII | Others | |
(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor targeting calpain I (μ-calpain) with a Ki value of 19 nM. It exhibits lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM)... | |||
T9686 | YH-53 | Others | |
YH-53 is a potent 3CLpro inhibitor, exhibiting K i values of 6.3 nM and 34.7 nM against SARS-CoV-1 3CLpro and SARS-CoV-2 3CLpro, respectively. This peptidomimetic compound, characterized by its unique benzothiazolyl keto... | |||
T35720 | 4’-hydroxy Atomoxetine Glucuronide (hydrate) | Others | |
4’-hydroxy Atomoxetine glucuronide is a metabolite of the norepinephrine transporter (NET) inhibitor atomoxetine .1It is formed from atomoxetine by glucuronidation of the intermediate metabolite 4-hydroxy atomoxetine.2 1... | |||
T36722 | Deltorphin II (trifluoroacetate salt) | Others | |
Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [3... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T75767 | Parasin I TFA | Others | |
Parasin I (TFA), a peptide derived from the 19 amino acids of histone H2A and isolated from catfish skin, exhibits antimicrobial activity [1]. |
カタログ番号 | 製品名 | Species | Expression System |
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TMPH-01579 | KRT19 Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. KRT19 Protein, Human, Recombinant (His & Myc) is expressed in Bac... | |||
TMPH-01580 | KRT19 Protein, Human, Recombinant (His) | Human | E. coli |
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. KRT19 Protein, Human, Recombinant (His) is expressed in E. coli e... | |||
TMPY-06651 | CD38 Protein, Mouse, Recombinant | Mouse | HEK293 Cells |
CD38 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 29.80 kDa and the accession number is NP_031672.2. | |||
TMPY-01158 | CD38 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD38 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is P56528. | |||
TMPK-00687 | Keratin, type I cytoskeletal 19 (310-399) Protein, Canine, Recombinant (His) | Canine | E. coli |
Keratin 19 (K19) belongs to the keratin family of proteins, which maintains structural integrity of epithelia. In cancer, K19 is highly expressed in several types where it serves as a diagnostic marker. | |||
TMPJ-01065 | Noggin/NOG Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept... | |||
TMPJ-01086 | CD244 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins have an extracellular domain (ECD) with two or four Ig-like d... | |||
TMPY-06885 | SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His) | ||
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... |
カタログ番号 | 製品名 | ||
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L9230 | ReFRAME Related Library | 3210 compounds | |
A unique collection of 3210 compounds for high-throughput screening and high-content screening, |