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TP1365L |
Parasin I acetate(219552-69-9 free base)
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Antibacterial
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Parasin I acetate is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus). |
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T6014 |
FRAX597
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PAK
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FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM). |
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T2078 |
Fimepinostat
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CUDC-907,PI3K/HDAC Inhibitor,CUDC 907 |
Apoptosis
,
PI3K
,
HDAC
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Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, C... |
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T62095 |
TRK-IN-19
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Others
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TRK-IN-19 (Compound I-10 ) is a potent inhibitor of TRK with IC50 values of 1.1 nM for TRKA and 5.3 nM for TRKAG595R. TRK-IN-19 has shown potential research value in cancer disease. |
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TP1365 |
Parasin I
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Parasin I is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus). |
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T126164 |
De-O-methylprosolanapyrone I
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Others
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De-O-methylprosolanapyrone I is a useful organic compound for research related to life sciences. The catalog number is T126164 and the CAS number is 1239892-19-3. |
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T82234 |
HCAIX-IN-19
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Others
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hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/hCAIX = 117). |
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T40893 |
Estrogen receptor modulator 6
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Others
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Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for... |
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TP1443 |
Parasin I (TFA)(219552-69-9,free)
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Parasin I (TFA) |
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Parasin I (TFA) is a 19-amino acid histone H2A-derived peptide isolated from the skin of the catfish, and shows antimicrobial activity[1]. |
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T61491 |
(R)-ND-336
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Others
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(R)-ND-336 is a highly potent and selective MMP-9 inhibitor, displaying a K i value of 19 nM. It also exhibits inhibitory activity against MMP-2 (K i = 127 nM) and MMP-14 (K i =119 nM). With its significant potential, (R... |
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T79648 |
CDK2-IN-19
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CDK
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CDK2-IN-19 (Compound 32) is a selective, orally active inhibitor of CDK2 (K i: 0.18 nM) that exhibits anticancer activity in mice with OVCAR3 tumors [1]. |
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T73372 |
GNE-2256
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Others
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GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM. |
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T79325 |
5-HT6 agonist 1
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5-HT Receptor
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Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting platelet aggregation. It demonstrates high metabolic stability [1]. |
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T79756 |
Beclin1-ATG14L interaction inhibitor 1
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Autophagy
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Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L. It impedes the formation of complex I in the lipid kinase VPS34, thus inhibiting aut... |
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T79373 |
A3AR agonist 2
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Adenosine Receptor
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Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM. This compound is utilized in research pertaining to inflammato... |
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T21949 |
Calpain Inhibitor XII
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Others
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(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor targeting calpain I (μ-calpain) with a Ki value of 19 nM. It exhibits lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM)... |
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T9686 |
YH-53
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Others
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YH-53 is a potent 3CLpro inhibitor, exhibiting K i values of 6.3 nM and 34.7 nM against SARS-CoV-1 3CLpro and SARS-CoV-2 3CLpro, respectively. This peptidomimetic compound, characterized by its unique benzothiazolyl keto... |
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T35720 |
4’-hydroxy Atomoxetine Glucuronide (hydrate)
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Others
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4’-hydroxy Atomoxetine glucuronide is a metabolite of the norepinephrine transporter (NET) inhibitor atomoxetine .1It is formed from atomoxetine by glucuronidation of the intermediate metabolite 4-hydroxy atomoxetine.2
1... |
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T36722 |
Deltorphin II (trifluoroacetate salt)
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Others
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Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [3... |
